Results 61 to 70 of about 27,546 (256)

Astigmatism Associated with Allergic Conjunctivitis in Urban School Children

Journal of Ophthalmology, 2019
Introduction. We first examined the association of an ocular refractive error with allergic conjunctivitis in school children and then examined this association in children attending a suburban school and an urban school. Methods.
Yangho Kim, Inbo Oh, Jiho Lee, Chang Sun Sim, Yeon Suh Oh, Ju-Hyang Lee   +5 more
doaj   +1 more source

Novel Bispecific Engagers Targeting the CεmX Domain of mIgE‐Expressing Cells

Allergy, EarlyView.
We developed bispecific TCE & NKCE targeting the CεmX domain of mIgE to eliminate IgE‐producing cells. Both constructs demonstrated potent, specific, dose‐dependent cytotoxicity and selective immune activation in vitro. These results highlight their promise as off‐the‐shelf, potentially curative therapeutics for IgE‐associated allergic diseases ...
Constantin Möller, Julia Hambach, Alessa Zoe Schaffrath, Thomas Eden, Sophia Cichutek, Anna Josephine Gebhardt, Natalie Tode, Ronald Maitschke‐Rajasekharan, Philipp Lewe, Sharon Qi, Susanne Witt, Marie Eggers, Nicola M. Tomas, Friedrich Haag, Friedrich Koch‐Nolte, Boris Fehse, Kristoffer Riecken   +16 more
wiley   +1 more source

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel [PDF]

, 2011
Background: There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature.
Anibarro B, B. Przybilla, de Larramendi CH, Eberlein-Konig B, F. Ruëff, Freeman GL, Lindemayr H, Majmudar V, Mayoral M, P. Schöpf, Perez, Singh AB, Stadtmauer G, Stockli SS, Stokes JR, T. Herzinger, Vidal C, Williams C   +17 more
core   +1 more source

Clinical characteristics of allergic conjunctivitis in the Southern region of Saudi Arabia: a cross-sectional study

Therapeutic Advances in Ophthalmology
Background: Allergic conjunctivitis is a prevalent ocular condition characterized by inflammation of the conjunctiva due to hypersensitivity reactions to various allergens.
Waleed ALDhabaan, Saleh Ghulaysi, Albatool Alqahtani, Eman Hurissi, Manar M. Alamri, Almuhannad G. Alnami, Ahmed H. Sumayli, Yahya A. Dhamri, Amani A. Mosleh, Ethar A. Khawaji, Abdullah A. Alshahrani, Abdulsalam S. Alfaifi, Saja M. Alghamdi   +12 more
doaj   +1 more source

A One‐Strength Dose Escalation Regimen for Birch Pollen SCIT Is Safe and Tolerable in Children, Adolescents, and Adults

Allergy, EarlyView.
This study evaluated safety and tolerability of birch pollen SCIT during dose escalation with a new One‐Strength regimen (3 injections, Strength B) compared to the Standard regimen (7 injections, Strengths A and B) in patients aged 5–65 years. Safety and tolerability were comparable between the two regimens in adults, adolescents, and adolescents, as ...
Marek Jutel, Ludger Klimek, Michael Gerstlauer, Dana Troyke, Kristina Duwensee, Christian Vogelberg   +5 more
wiley   +1 more source

Syndromic surveillance to assess the potential public health impact of the Icelandic volcanic ash plume across the United Kingdom, April 2010 [PDF]

, 2010
The Eyjafjallajökull volcano in Iceland erupted on 14 April 2010 emitting a volcanic ash plume that spread across the United Kingdom and mainland Europe.
Catchpole, M., Elliott, A.J., Harcourt, S., Ibbotson, S., Kavanagh, K., Kibble, A., Loveridge, P., McCloskey, B., McMenamin, J., Murray, V., Pnaiser, R., Ramsay, C.N., Robertson, C., Singh, N., Smith, G.E., Smith, S.   +15 more
core  

IgE Sensitization to Inhalant Allergens and Its Association with Allergic Diseases in Adults

Iranian Journal of Allergy, Asthma and Immunology, 2018
Allergic sensitization to inhalant allergens could be considered as a predictor in allergic diseases. The objective of this study was to assess IgE-mediated sensitization to inhalant allergens in allergic and non-allergic adults as well as the evaluation
Raheleh Shokouhi Shoormasti, Mohammad Reza Fazlollahi, Anoshirvan Kazemnejad, Behnoosh Tayebi, Fatemeh Nadali, Maryam Sharif Shoushtari, Shamim Khandan Alamdari, Majid Moslemi, Masoud Movehdi, Adriano Mari, Zahra Pourpak, Mostafa Moin   +11 more
doaj  

Patient‐Perceived Benefits of Named‐Patient Product Sublingual Immunotherapy in Allergic Rhinitis and Asthma: Primary Results From the ERAPP Real‐World Cohort Study

Allergy, EarlyView.
Evaluation en vie Réelle de l'Allergo‐Prescription en Pratique (ERAPP) is a large, prospective, real‐world cohort of children and adults initiating named‐patient product sublingual immunotherapy (NPP‐SLIT) in France. More than 80% of patients reported a clinically meaningful, expectation‐anchored benefit (Patient Benefit Index ≥ 1) at 12–15 months. The
Davide Caimmi, Abdelilah Abouelfath, Régis Lassalle, Séverine Lignot‐Maleyran, Emmanuelle Bignon, Patrick Blin, Evangéline Clark, Julien Cottet, Laure Carcaillon‐Bentata, Pascal Demoly   +9 more
wiley   +1 more source

Hydrocortisone concentration influences time to clinically significant healing of acute inflammation of the ocular surface and adnexa – results from a double-blind randomized controlled trial [PDF]

, 2014
BACKGROUND: The efficacy of topical ophthalmic corticosteroids depends upon small modifications in preparations, such as drug concentration. The aim of this study was to confirm that hydrocortisone acetate (HC-ac) ophthalmic ointments of 2.5% and 1% are ...
Dorothea Groß, Ludmila Sukhina, Matthias Merzbacher, Nikolai Nikitin, Nikolay Sergiyenko, Pavel Bezdetko, Ralf Kohnen, Yuriy Kovalenko   +7 more
core   +3 more sources