Results 41 to 50 of about 37,073 (243)

Severe Nerve Enlargement in SOS2‐Related Noonan Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Noonan syndrome is a genetic multisystem congenital disorder, caused by pathogenic variants in genes that encode components of the RAS/MAPK signaling pathway. Pathogenic variants in SOS2 represent less than 2% of cases with NS. The phenotype includes a particularly high prevalence (65%) of lymphatic disease. Recently, severe nerve enlargements
Erika Leenders, Fieke Draaisma, Corrie E. Erasmus, Catelijne Coppens, Lotte E. R. Kleimeier, Melanie Burgers, Tuula Rinne, Martin Zenker, Laura Mazzanti, Wesley Reintjes, Nens van Alfen, Jos M. T. Draaisma   +11 more
wiley   +1 more source

The ocular crisis: Conjunctivitis in Karachi

Journal of the Pakistan Medical Association
Dear Editor, Conjunctivitis, commonly referred to as Pink Eye, is an eye condition characterized by inflammation of the conjunctiva, leading to a pink or red discoloration due to dilated conjunctival blood vessels.
Muhammad Farhan, Sadia Tahir, Faiza Ahsan   +2 more
doaj   +1 more source

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle, Nand Singh, Denis Gossen, Annick Janin, Raman Sharma, Anthony Cahn, Rachel A. Gibson, Somasekhara R. Menakuru, Erin Lambourne, Tom Dove, Francisco‐Javier Gamo, Laura Sanz, Benoit Bestgen, Stephan Chalon   +13 more
wiley   +1 more source

Altered hyaluronic acid content in tear fluid of patients with adenoviral conjunctivitis

Anais da Academia Brasileira de Ciências, 2015
The adenoviral conjunctivitis is one of the biggest causes of conjunctival infection in the world. Conjunctivitis causes relatively nonspecific symptoms, as hyperaemia and chemosis.
JULIANA L. DREYFUSS, CAIO V. REGATIERI, BRUNO COELHO, JOSÉ B. BARBOSA, DENISE DE FREITAS, HELENA B. NADER, JOÃO R. MARTINS   +6 more
doaj   +1 more source

Coronavirus disease 2019 presenting with conjunctivitis as the first symptom

Eye, 2020
Coronavirus disease 2019 (COVID-19) is a public health emergency that has reached the proportions of a pandemic [1]. At present, Italy has been one of the most affected Countries with the majority of cases documented in Northern Italy, especially in the ...
G. Casalino, G. Monaco, Paolo Plinio Di Sarro, A. David, A. Scialdone   +4 more
semanticscholar   +1 more source

Acute myocarditis according to age: Presentation, management and early outcomes

ESC Heart Failure, EarlyView.
MIS, multisystem inflammatory syndrome; MRE, myocarditis‐related events (within 30 days included all‐cause death, cardiogenic shock, cardiac arrest, ventricular arrhythmias or complete AV block). Abstract Aims Acute myocarditis (AM) is a rare but severe disease affecting patients of all ages. Large multicentric studies comparing children and adults are
Clément Karsenty, Paul Vignaud, Clara Brusq, Pamela Moceri, Pascal Lim, Edouard Gerbaud, Olivier Lairez, Coline Lelarge, Caroline Ovaert, Claire Bouleti, Oscar Werner, Vanina Bongard, Thibaud Genet, Laurent Bonnemains, Christophe Tron, Elise Barre, Margaux Boddaert, Jacques Mansourati, Chérine Benzouid, François Roubille, Hadi Khachab, Sabrina Uhry, Ariel Cohen, Benoit Lattuca, Sylvie Di Filippo, Clément Delmas   +25 more
wiley   +1 more source

Vision Changes After Head and Neck Cancer Treatment

Head &Neck, EarlyView.
ABSTRACT Background Literature about ocular toxicity after head and neck cancer (HNC) treatment is scarce. This study aimed to describe visual function and ocular symptoms among HNC patients. Methods The study used a cross‐sectional design. Two surveys, The National Eye Institute Visual Functioning Questionnaire (NEI‐VFQ) and an Ocular Symptom Scale ...
Hsiao‐Lan Wang, Megan Heskett, Peng Li, Laura Dreer, David Vance, Susan McCammon, Kailei Yan, Amanda Elliott   +7 more
wiley   +1 more source

OBSERVATIONS ON CONJUNCTIVITIS. [PDF]

The Lancet, 1910
n ...
openaire   +3 more sources

Association of Tralokinumab and Adalimumab: Good Tolerance and Efficacy in a Case of Severe Atopic Dermatitis and Juvenile Idiopathic Arthritis

JEADV Clinical Practice, EarlyView.
ABSTRACT Atopic dermatitis is a chronic inflammatory and pruritic skin disease. The combination of tralokinumab with adalimumab in the treatment of inflammatory diseases had not yet been documented. It appears promising for treating severe atopic dermatitis in patients with juvenile idiopathic arthritis, offering significant improvement in skin ...
F. Rakotonandrasana, E. Puzenat, A. Ducournau, D. Popescu   +3 more
wiley   +1 more source

Conjunctivitis among Rural and Urban School Children in Erbil Governorate/ Iraq

Diyala Journal of Medicine, 2020
Background: In children conjunctivitis is the most widespread ocular surface disease. It is referred to any inflammatory condition of the conjunctiva.
Nabaz Fisal Shakir Agha
doaj   +2 more sources