Results 31 to 40 of about 12,532 (250)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Türk Kültürü ve Hacı Bektaş Velî Araştırma Dergisi, 2021 Cönk ve mecmualarda yer alan sınırlı sayıda şiirleri ile tanınan Seher Abdal, 15. yüzyılın ikinci yarısı ile 16. yüzyılın ilk yarısında yaşamış, telif ve tercüme eserleri olan bir şairdir.
Meriç HARMANCI
doaj
Acta Chimica Slovenica, 2020 The effect of homogenization, ultrasound and microwave extraction methods and conditions on fucoxanthin content, total phenolic content and antioxidant activity of extracts obtained from Phaeodactylum tricornutum were investigated in this study.
Saniye Akyıl +6 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Pharmaceutical Biology, 2017 Context: Algae have gained importance in cosmeceutical product development due to their beneficial effects on skin health and therapeutical value with bioactive compounds.
Seda Gunes +3 more
doaj +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Holes in the Infrastructure of Global Hyperelliptic Function Fields [PDF]
, 2009 We prove that the number of "hole elements" $H(K)$ in the infrastructure of a hyperelliptic function field $K$ of genus $g$ with finite constant field $\F_q$ with $n + 1$ places at infinity, of whom $n' + 1$ are of degree one, satisfies $|\frac{H(K ...
Fontein, Felix
core
Ricci curvature bounds for warped products [PDF]
, 2013 We prove generalized lower Ricci curvature bounds for warped products over complete Finsler manifolds. On the one hand our result covers a theorem of Bacher and Sturm concerning euclidean and spherical cones.
Ketterer, Christian
core +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
La problemática de las partes y el contenido de la legitimación activa en la cuestión de inaplicabilidad por inconstitucionalidad de la ley [PDF]
, 2010 El presente trabajo aborda la justificación y el contenido de la legitimación activa en el proceso de inaplicabilidad por inconstitucionalidad de la ley en Chile, en una perspectiva de contexto de un sistema concentrado y concreto, para llegar ...
Pica Flores, Rodrigo
core +1 more source