Results 61 to 70 of about 1,339 (249)
Advanced Science, EarlyView.Glutamine deprivation triggers transient DNA damage yet activates adaptive repair in hepatocellular carcinoma cells. We identify TRIB3 as a stress‐induced nuclear scaffold that associates with DDX5 and G‐quadruplex DNA atBRCA1 andRAD51AP1 promoters. TRIB3 loss increases G4 accumulation, suppresses HR gene transcription, elevates γ‐H2A.X, and sensitizes
Qiang Ji +10 more
wiley +1 more source
Working Paper 21: Managing Coarse Woody Debris in Fire-adapted Southwestern Forests [PDF]
, 2008 Fire-adapted forested ecosystems in the Southwest evolved with a continual flux of downed woody material, a structural component that is considered essential to a properly functioning forest ecosystem.
Brewer, D.
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Advanced Science, EarlyView.A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu +9 more
wiley +1 more source
Comparison of Tree Condition and Value for City Parks and Stephen F. Austin State University in Nacogdoches, Texas, U.S. [PDF]
, 2014 Trees in landscapes are valued for physical as well as aesthetic benefits and biodiversity. Trees on a university campus and in city parks also help to provide an environment in which students and visitors can study and relax.
Hung, I-Kuai +4 more
core +1 more source
Advanced Science, EarlyView.The RNA G‐quadruplexes formed at the 5'‐end of the RNA component of human telomerase possess extreme slow unfolding rate, rendering them resistant to nuclease degradation. The helicase DHX36 overcame this kinetic barrier and significantly reduced the folded fraction.
Qun Luo +5 more
wiley +1 more source
Accumulation and distribution of 40K in the chaga mushroom. [PDF]
Mycoscience, 2021 Victor D, Peter S.
europepmc +1 more source
Advanced Science, EarlyView.In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
Findings of the Association for Computational Linguistics: ACL 2025Knowledge Editing (KE) aims to adjust a Large Language Model's (LLM) internal representations and parameters to correct inaccuracies and improve output consistency without incurring the computational expense of re-training the entire model. However, editing commonsense knowledge still faces difficulties, including limited knowledge coverage in existing
Zhang, Liyu +3 more
openaire +2 more sources
A Plan for Igniting Nigeria’s Industrial Revolution [PDF]
, 2016 The Industrialization of countries is in every way influenced by forerunner nations. This is exemplified in Western Europe’s copying of Britain’s technology and manufacturing systems. This work presents a study of the industrialization of nations such as
Azeta, Joseph +4 more
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