Results 101 to 110 of about 2,522,495 (283)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Dental Images' Segmentation Using Threshold Connected Component Analysis. [PDF]
Comput Intell Neurosci, 2021 Majanga V, Viriri S.
europepmc +1 more source
Decomposing Infinite 2-Connected Graphs into 3-Connected Components [PDF]
The Electronic Journal of Combinatorics, 2004 In the 1960's, Tutte presented a decomposition of a 2-connected finite graph into 3-connected graphs, cycles and bonds. This decomposition has been used to reduce problems on 2-connected graphs to problems on 3-connected graphs. Motivated by a problem concerning accumulation points of infinite planar graphs, we generalize Tutte's decomposition to ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Connected components of complex divisor functions [PDF]
Journal of Number Theory, 2018 For any complex number $c$, define the divisor function $ _c\colon\mathbb N\to\mathbb C$ by $\displaystyle _c(n)=\sum_{d\mid n}d^c$. Let $\overline{ _c(\mathbb N)}$ denote the topological closure of the range of $ _c$. Extending previous work of the current author and Sanna, we prove that $\overline{ _c(\mathbb N)}$ has nonempty interior and has ...
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Aging of Chinese bony orbit: automatic calculation based on UNet++ and connected component analysis. [PDF]
Surg Radiol Anat, 2022 Pan L +6 more
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Ultrasound segmentation-guided edge artifact reduction in diffuse optical tomography using connected component analysis. [PDF]
Biomed Opt Express, 2021 Li S, Zhang M, Zhu Q.
europepmc +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source