Results 61 to 70 of about 5,986,669 (282)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

ALGORITHMS FOR MINIMUM CONNECTED CAPACITATED DOMINATING SET PROBLEM

open access: yes, 2011
Connected dominating set (CDS) has been proposed as the virtual backbone to alleviate the broadcasting storm in wireless sensor network. Most recent research has extensively focused on the construction of connected dominating set.
WEIPING SHANG, XIUMEI WANG
core   +1 more source

Connected Dominating Set & Related Problems

open access: yes, 2019
Ερευνούμε δύο εκδοχές του προβλήματος του Συνδεδεμένου Κυρίαρχου Συνόλου (ΣΚΣ), τα προβλήματα του Μερικώς Συνδεδεμένου Κυρίαρχου Συνόλου (ΜΣΚΣ) και του Μπάτζετ Συνδεδεμένου Κυρίαρχου Συνόλου (ΠΣΚΣ).
Yfantis Filippos   +3 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Distributed Energy-Efficient Approaches for Connected Dominating Set Construction in Wireless Sensor Networks

open access: yesInternational Journal of Distributed Sensor Networks, 2014
Energy efficiency is one of the major issues in wireless sensor networks (WSNs) and their applications. Distributed techniques with low message and time complexities are expected in WSNs. Connected dominating sets (CDSs) have been widely used for virtual
Najla Al-Nabhan   +2 more
doaj   +1 more source

New bound on MIS and MIN-CDS for a unit ball graph

open access: yesICT Express, 2017
The size of the maximum independent set (MIS) in a graph G is called the independence number. The size of the minimum connected dominating set (MIN-CDS) in G is called the connected domination number.
D.A. Mojdeh, M. Ghanbari, M. Ramezani
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Minimum Connected Dominating Set and Backbone of a Random Graph [PDF]

open access: yes, 2023
We study the minimum dominating set problem as a representative combinatorial optimization challenge with a global topological constraint. The requirement that the backbone induced by the vertices of a dominating set should be a connected subgraph makes ...
Zhou, Hai-Jun, Habibulla, Yusupjan
core   +1 more source

A Distributed Design for Minimum 2-Connected m-Dominating Set in Bidirectional Wireless Ad-Hoc Networks

open access: yesTsinghua Science and Technology, 2012
Wireless ad-hoc network is widely used in many fields for its convenience and outstanding suitability. Because of the inherent lack of infrastructure and the nature of wireless channels, people select the k-Connected m-Dominating Set ((k, m)-CDS) in a ...
Xiaofeng Gao, Bosheng Xu, Jun Li
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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