Results 51 to 60 of about 302,672 (265)

Connected even factors in k-tree

open access: yesOpen Mathematics, 2020
Abstract A connected even [ 2 , 2 s ] {[}2,2s]
Li Yinkui   +4 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Connecting the Sustainable Development Goals to firm-level sustainability and ESG factors: The need for double materiality

open access: yesBusiness Research Quarterly, 2023
In this essay, we connect the United Nations’ Sustainable Development Goals (SDGs)—an extensive collection of society-level goals and targets aimed at addressing grand challenges and achieving global sustainability by 2030—to firm-level sustainability ...
Javier Delgado-Ceballos   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Nationality in International Private Law

open access: yesBratislava Law Review
Nationality, lex patriae, continues to play a significant role as a connecting factor in resolving private-law relationships involving a foreign element, both in the context of conflict-of-law rules and in determining international jurisdiction ...
Dominika Moravcová
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Digital pathways connecting social and biological factors to health outcomes and equity

open access: yesnpj Digital Medicine
Digital pathways extend conventional connections between social and biological factors and health outcomes, significantly influencing health equity. Data representation bias and distribution shifts are key mechanisms through which determinants of health ...
Yan Cui
doaj   +1 more source

Experimental Study on Seismic Behavior of Steel Frames with Infilled Recycled Aggregate Concrete Shear Walls

open access: yesApplied Sciences, 2019
Experiments were performed on four specimens of steel frames with infilled recycled aggregate concrete shear walls (SFIRACSWs), one specimen of infilled ordinary concrete wall, and one pure-steel frame were conducted under horizontal low cyclic loading ...
Lijian Sun, Hongchao Guo, Yunhe Liu
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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