Results 121 to 130 of about 2,175,475 (311)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Ohio potteries of the 19th century map
, 1940 Map of Ohio showing the location and distribution of 348 Ohio potteries of the 19th century, prepared by the Ohio State Archaeological and Historical Society and drawn by C.E. Hamm.
C.E. Hamm (Artist); Ohio State Archaeological and Historical Society;
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The Presence of a Pet Dog Is Associated with a More Balanced Response to a Social Stressor
StressesAcute and chronic stress each have physical manifestations in the human body that can lead to many negative health impacts. Today, reported stress levels worldwide are at an all-time high, spurring the search for non-pharmaceutical interventions to ...
Jaci Gandenberger +6 more
doaj +1 more source
Pioneer Statue at base of Fort Recovery monument
Statue of a pioneer at the base of Fort Recovery Monument, Mercer County, Ohio. Fort Recovery, built in 1792, was the site of Major General Arthur St. Clair defeat by an Indian Confederacy under the leadership of Shawnee chief Weyapiersenwah (Blue Jacket)
Ohio History Connection
core
World's Columbian Exhibition award
, 1893 Award from the World's Columbian Commission to the Ohio Archaeological and Historical Society (now the Ohio History Connection) for its display illustrating the American Indian Moundbuilders of the Ohio Territory, exhibited at the International ...
United States Treasury Department (Engraver)
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
CONTEXT/OBJECTIVES: Establishing human connection is critical during serious illness conversations, however the sensory and relational environment of telehealth may require innovative communication practices for clinicians, patients, and families to do ...
Tarbi, Elise C
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 1918 This is a photograph of the W.P. Snyder Jr., a steam-powered paddleboat launched around 1918. The W.P. Snyder, Jr. is located at the Ohio River Museum, an Ohio History Connection site in Marietta, Ohio.
core