Results 101 to 110 of about 131,872 (281)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Diffusion Coefficient of Urate for Human Connective Tissue Membrane

Experimental Biology and Medicine, 1956
SummaryDeterminations were made at 374dGC by the method of Johnsen and Kirk of the diffusion coefficient of urate for a human connective tissue membrane (cerebellar tentorium). The urate analyses were performed by enzymatic differential spectrophotometry. The average coefficient value found in experiments on 10 samples was 0.000155.
T J, LAURSEN, R S, LAURSEN, J E, KIRK
openaire   +2 more sources

Impact of Plasma p‐tau181 on Cognition, Motor Phenotypes, and Disease Course in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Phosphorylated tau181 (p‐tau181), an Alzheimer's disease biomarker, was recently evaluated in amyotrophic lateral sclerosis (ALS). We investigated plasma p‐tau181 in 202 ALS/ALS‐FTD patients and 94 healthy controls, assessing cognitive performance, motor function, and longitudinal dynamics.
Elisabeth Kasper, Annaliis Lehto, Nina Nordmann, Oliver Peters, Julian Hellmann, Josef Priller, Eike Jakob Spruth, Gabor C. Petzold, Ina Vogt, Patrick Weydt, Sarah Bernsen, Elisabeth Dinter, Björn Falkenburger, René Günther, Emrah Düzel, Wenzel Glanz, Matthis Synofzik, Lukas Beichert, Annika Spottke, Michael Wagner, Frederic Brosseron, Matthias C. Schmid, Anja Schneider, Stefan Teipel, Johannes Prudlo, Andreas Hermann   +25 more
wiley   +1 more source

Recurrence relations for the connection coefficients of orthogonal polynomials of a discrete variable on the lattice x(s) = q2s

, 1998
We give explicitly recurrence relations satisfied by the connection coefficients between two families of the classical orthogonal polynomials of a discrete variable on a non-uniform lattice x(s) = q2s (i.e., the q-analogues of Charlier, Meixner ...
Lewanowicz, Stanislaw
core   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

Alexander and Jones polynomials of weaving 3-braid links and Whitney rank polynomials of Lucas lattice

Heliyon
In this paper, a connection is established between the Jones polynomial of generalized weaving knots of type W(3,n,m) and the Chebyshev polynomial of the first kind.
Mark E. AlSukaiti, Nafaa Chbili
doaj   +1 more source

Coupling coefficients of suq(1,1) and multivariate q-Racah polynomials

Nuclear Physics B, 2018
Gasper & Rahman's multivariate q-Racah polynomials are shown to arise as connection coefficients between families of multivariate q-Hahn or q-Jacobi polynomials. The families of q-Hahn polynomials are constructed as nested Clebsch–Gordan coefficients
Vincent X. Genest, Plamen Iliev, Luc Vinet   +2 more
doaj   +1 more source

Some New Connection Relations Related to Classical Orthogonal Polynomials

Journal of Mathematics, 2020
In this paper, we deal with a problem of positivity of linear functionals in the linear space ℙ of polynomials in one variable with complex coefficients.
Wathek Chammam, Wasim Ul-Haq
doaj   +1 more source

Minimal recurrence relations for connection coefficients between classical orthogonal polynomials: Discrete case

, 1997
We present a simple approach in order to compute recursively the connection coefficients between two families of classical (discrete) orthogonal polynomials (Charlier, Meixner, Kravchuk, Hahn), i.e., the coefficients Cm(n) in the expression Pn(X)=∑nm=0Cm(
Godoy, E., Area, I., Ronveaux, A., Zarzo, A.   +3 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source