Results 111 to 120 of about 365 (231)

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

RRP9 Promotes Esophageal Squamous Cell Carcinoma Progression through E2F1 Transcriptional Regulation of CDK1

open access: yesAdvanced Biology, EarlyView.
The study reveals that RRP9 is abnormally highly expressed in ESCC tissues and is closely associated with poor prognosis in patients. Furthermore, it is found that RRP9 promotes ESCC progression through enhancing the E2F1‐mediated transcriptional regulation of CDK1.
Gang He   +14 more
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

open access: yesAdvanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani   +4 more
wiley   +1 more source

3D‐Printed Architected Material for the Generation of Foam‐Based Protective Equipment

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates 3D‐printed architected structures as alternatives to traditional foams in protective gear. It focuses on customizing impact strength and damping through design and manufacturing integration. Testing shows these structures outperform conventional foams, offering enhanced customizability, lower weight, and tunable performance ...
Ali Zolfagharian   +5 more
wiley   +1 more source

From Nature to Engineering: Mortar Volume and Interfacial Mechanics in Bioinspired Ceramics

open access: yesAdvanced Engineering Materials, EarlyView.
Inspired by natural armors like nacre, this study explores how varying the volume fraction of the soft mortar layer impacts the interfacial strength and toughness of bioinspired ceramics. Experimental and computational analysis reveals that higher mortar volumes increase energy dissipation but reduce interfacial stiffness, offering insights for ...
Ehsan Azad   +4 more
wiley   +1 more source

Microstructural Evolution and Mechanical Property Degradation of Sn0.5Ag0.7Cu5Bi Solder Joints with High Indium Alloying

open access: yesAdvanced Engineering Materials, EarlyView.
This study identifies 12 wt% indium (In) as the optimal composition for Sn0.5Ag0.7Cu5Bi solder joints, achieving 87% ductile fracture and 81% suppression of intermetallic compound (IMC) growth versus 4 wt% In. High‐In alloys (15–17 wt%) show abnormal IMC thickening due to thermal activation.
Liuwei Wang   +11 more
wiley   +1 more source

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