Results 91 to 100 of about 105,811 (271)

Connections on the path bundle of a principal fiber bundle

open access: yesDifferential Geometry and its Applications, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

About an analogue of Neifeld’s connection on the space of centred planes with two-index basic-fibre forms

open access: yesДифференциальная геометрия многообразий фигур, 2018
Space П of centred m-planes is considered in the projective space . Prin­cipal fiber bundle is arised above it. Two-index structural forms of the principal fiber are included also into structure of basic forms.
O. Belova
doaj  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

On some flat connection associated with locally symmetric surface

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2014
For every two-dimensional manifold M with locally symmetric linear connection nabla, endowed also with nabla-parallel volume element, we construct a flat connection on some principal fibre bundle P(M,G).
Maria Robaszewska
doaj  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

On the Invariant and Geometric Structure of the Holomorphic Unified Field Theory

open access: yesAxioms
We present the invariant structure of a Holomorphic Unified Field Theory in which gravity and gauge interactions arise from a single geometric framework.
John W. Moffat, Ethan James Thompson
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

A cohomological description of connections and curvature over posets

open access: yes, 2006
What remains of a geometrical notion like that of a principal bundle when the base space is not a manifold but a coarse graining of it, like the poset formed by a base for the topology ordered under inclusion? Motivated by finding a geometrical framework
Roberts, John E., Ruzzi, Giuseppe
core  

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