Results 91 to 100 of about 105,811 (271)
Connections on the path bundle of a principal fiber bundle
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openaire +2 more sources
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Space П of centred m-planes is considered in the projective space . Principal fiber bundle is arised above it. Two-index structural forms of the principal fiber are included also into structure of basic forms.
O. Belova
doaj
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
On some flat connection associated with locally symmetric surface
For every two-dimensional manifold M with locally symmetric linear connection nabla, endowed also with nabla-parallel volume element, we construct a flat connection on some principal fibre bundle P(M,G).
Maria Robaszewska
doaj
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
On the Invariant and Geometric Structure of the Holomorphic Unified Field Theory
We present the invariant structure of a Holomorphic Unified Field Theory in which gravity and gauge interactions arise from a single geometric framework.
John W. Moffat, Ethan James Thompson
doaj +1 more source
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
A cohomological description of connections and curvature over posets
What remains of a geometrical notion like that of a principal bundle when the base space is not a manifold but a coarse graining of it, like the poset formed by a base for the topology ordered under inclusion? Motivated by finding a geometrical framework
Roberts, John E., Ruzzi, Giuseppe
core

