Results 71 to 80 of about 3,456,047 (292)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

About an analogue of Neifeld’s connection on the space of centred planes with one-index basic-fibre forms

open access: yesДифференциальная геометрия многообразий фигур, 2019
This research is realized by Cartan — Laptev method (with prolonga­tions and scopes, moving frame and exterior forms). In this paper we con­sider a space П of centered m-planes (a space of all centered planes of the dimension m). This space is considered
Е. Belova, O. Belova
doaj   +1 more source

Defining the mobility range of a hinge-type connection using molecular dynamics and metadynamics.

open access: yesPLoS ONE, 2020
A designed disulfide-rich β-hairpin peptide that dimerizes spontaneously served as a hinge-type connection between proteins. Here, we analyze the range of dynamics of this hinge dimer with the aim of proposing new applications for the DNA-encodable ...
Philip Horx, Armin Geyer
doaj   +1 more source

A geometric approach to discrete connections on principal bundles

open access: yesJournal of Geometric Mechanics, 2013
This work revisits, from a geometric perspective, the notion of discrete connection on a principal bundle, introduced by M. Leok, J. Marsden and A. Weinstein. It provides precise definitions of discrete connection, discrete connection form and discrete horizontal lift and studies some of their basic properties and relationships. An existence result for
Fernández, J., Zuccalli, Marcela
openaire   +3 more sources

Prescribing the curvature of a principal bundle connection

open access: yes, 1989
This thesis considers the problem of prescribing curvature for connections on principal bundles. As is well known, a connection on a principal bundle uniquely determines the curvature of that bundle.
Talvacchia, Janet Claire
core  

Full-field optical coherence tomography using a fibre imaging bundle [PDF]

open access: yes, 2006
An imaging fibre bundle is demonstrated for spatially-multiplexed probe beam delivery in OCT, with the aim of eliminating the mechanical scanning currently required at the probe tip in endoscopic systems.
H. D. Ford   +3 more
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Project IMPACT pilot report: feasibility of implementing a hospital-to-home transition bundle.

open access: yes, 2017
BACKGROUND AND OBJECTIVES: To improve hospital to home transitions, a 4-element pediatric patient-centered transition bundle was developed, including: a transition readiness checklist; predischarge teach-back education; timely and complete written ...
Cooperberg, David   +10 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

World War exhibit at Ohio State Museum

open access: yes, 1940
This photograph shows the "Ohio in the Wars" room at the Ohio State Museum. Seen browsing the exhibit are Dr. William Overman, Curator of History, and Miss Mary Poster, a member of the museum staff.
Ohio History Connection
core  

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