Results 51 to 60 of about 459,615 (259)

Feeling connected to nature: validation of the connectedness to nature scale in the Italian context

open access: yesFrontiers in Psychology, 2023
Environmental issues are at the center of the political and cultural debate, representing one of the greatest challenges of our century. Sustainability and pro-environmental conducts are recognized as increasingly urgent to address the decay of ecosystems.
Chiara Lovati   +11 more
openaire   +4 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Les modes d’appropriations de l’espace « vague » sur le littoral français

open access: yesGéographie et Cultures, 2011
The surf riding experiencing known constant development over the past forty years and the entire French coastline is invested by riders: surfers, of course, but also windsurfers and kitesurfers.
Guillaume Mariani
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

open access: yesFEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto   +6 more
wiley   +1 more source

Compte rendu de la passion. À propos de la lecture religieuse de Phèdre de Racine

open access: yesStudia Romanica Posnaniensia, 2018
The classicist, Christianized iteration of the myth of Phaedra demonstrates the particular nature of the tensions between Christian metaphysics and social morality. Based on the Pascal’s paradox of the right-eous sinner.
Patrycja Tomczak
doaj   +1 more source

Nature-focused livestreams: Connecting people to nature and to each other

open access: yesCurrent Opinion in Psychology
Engaging with nature has been found to have a range of benefits across the biopsychosocial and spiritual domains of well-being. Nature-focused livestreams (NFLs) offer an alternative to physically engaging with nature and serve as a window to nature as society has become more urbanized and has increasingly moved indoors.
Keith A. Anderson   +4 more
openaire   +2 more sources

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