Results 51 to 60 of about 91,202,407 (238)
Creativity Studies, 2023 There has been research on the significance of placemaking as a process for user health and well-being and how that affects their way of life in urban planning and development.
Shanta Pragyan Dash, N. Lakshmi Thilagam
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
People and NatureReconnecting young people with nature is increasingly recognized as critical for human and planetary well‐being, yet opportunities for youth to form these connections are shrinking.
Bryn Spielvogel +3 more
doaj +1 more source
Education SciencesIn Australia and around the world, young students are increasingly experiencing declines in wellbeing, engagement, and sense of belonging. These trends are accompanied by rising anxiety and social disconnection that affect learning and development.
Alexandra Harper +2 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Les modes d’appropriations de l’espace « vague » sur le littoral français
Géographie et Cultures, 2011 The surf riding experiencing known constant development over the past forty years and the entire French coastline is invested by riders: surfers, of course, but also windsurfers and kitesurfers.
Guillaume Mariani
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Frontiers in Psychology, 2020 Zoos attract millions of visitors every year, many of whom are schoolchildren. For this reason, zoos are important institutions for the environmental education of future generations.
Matthias Winfried Kleespies +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A nature love affair: exploring education as a means to foster connection to nature in college students [PDF]
, 2023 Connection to nature (CTN) has been linked to improved health and well-being and an increase in an individual's pro-environmental behaviors. CTN is often thought to be developed in one's childhood, but some studies have refuted this claim by studying CTN
NC DOCKS at Western Carolina University +1 more
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