Results 31 to 40 of about 118,773 (236)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Negation Jangan from a Lexical Functional Perspective [PDF]
, 2016 This paper is an investigation into the properties of the negation jangan in the framework of Lexical-Functional Grammar. The analysis shows that the negation jangan can negate verbs functioning as predicate in a sentence.
Truly Almendo Pasaribu +1 more
core +1 more source
EPiC: A Four-Valued Evidential Constraint Calculus for First-Order Reasoning
AxiomsThis article introduces the Evidence Propagation Calculus (EPiC), an operational framework for first-order reasoning built on a simple but productive observation: familiar inference patterns such as Modus Ponens and Modus Tollens behave like the movement
José Oscar Olmedo-Aguirre +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Negative inversion, negative concord and sentential negation in the history of English [PDF]
, 2012 It is claimed in van Kemenade (2000: 62) that clauses with initial negative constituents are a context in which subject–verb inversion occurs throughout the history of English.
Wallage, Phillip
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 This chapter provides the state-of-the-art around expletive negation (EN), by discussing: (i) the relationship between EN and negative concord; (ii) EN as a real negation; (iii) EN as a special formative linked to an additional evaluative/expressive ...
Delfitto, Denis
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2015 This chapter describes negation in Skolt Saami in a typological perspective. In the standard negation construction, the negative marker is a negative auxiliary verb and the lexical verb appears in a non-finite form.
Matti Miestamo +3 more
core +1 more source
Eye-movements and ERPs reveal the time course of processing negation and remitting counterfactual worlds [PDF]
, 2008 The ability to update our current knowledge using contextual information is a vital process during every-day language comprehension. To understand a negated statement, readers are required to cancel real-world expectations, but are not explicitly ...
Ferguson, Heather J. +2 more
core +1 more source