Results 71 to 80 of about 118,773 (236)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Negation in South Saami

open access: yes, 2015
Standard negation in South Saami utilizes a negative auxiliary, which has two tenses (present and preterite), and connegative forms of the lexical verb.
Inaba, Nobufumi,, Blokland, Rogier,
core   +1 more source

215Linguistic connections in the syntax of negation: The Greek and Latin Gospels

open access: yes
The Latin Vulgata version of the Gospels is compared to the Greek original for possible translation effects in the expression of negation, well known as a vulnerable domain for contact. Specifically, this paper focuses on negative concord patterns which are present in the Greek original but are expected to be ungrammatical in Latin.
openaire   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Negation in standard and Kuwaiti Arabic [PDF]

open access: yes, 2012
Restriction data tranferred 2014-07-01T11:35:44-05:00 Original Data Group with Access Administrator Release Date: 2014-09-18 16:27:16 UTC Reason: Author requested closed access (OA after 2yrs) in Vireo ETD systemItem marked as restricted to the ...
Alsalem, Eman
core  

What is Negation in a System 2020?

open access: yes, 2021
peer reviewedThe notion of negation is basic to any formal or informal logical system. When any such system is presented to us, it is presented either as a system without negation or as a system with some form of negation.
GABBAY, Dov M.
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Negation in weak positional calculi [PDF]

open access: yes, 2013
Four weak positional calculi are constructed and examined. They refer to the use of the connective of negation within the scope of the positional connective “R” of realization.
Tkaczyk, Marcin
core  

Ricoeur and the negation of happiness

open access: yes, 2013
Ricoeur lectured and wrote for over twenty years on negation ('Do I understand something better if I know what it is not, and what is not-ness?') and never published his extensive writings on this subject.
Scott-Baumann, Alison
core   +1 more source

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