Results 241 to 250 of about 4,769,883 (431)

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.
Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang   +3 more
wiley   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen   +6 more
wiley   +1 more source

Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders. [PDF]

open access: yesFront Neurol
Ruhoy IS   +6 more
europepmc   +1 more source

Persistent Connective Tissue in Fundi

open access: bronze, 1929
Achmad Adam, M. S. Mayou
openalex   +1 more source

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