A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
Undifferentiated connective tissue disease: the diagnoses critically revised-experience of a single center. [PDF]
Cavazzana I+7 more
europepmc +1 more source
Pulse radiolysis and spectral studies of the interaction of cetylpyridinium chloride and Methylene Blue with connective-tissue glycosaminoglycans and related compounds [PDF]
Julie Davies+3 more
openalex +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Acute Bowel Perforation Post-Bowel Preparation in a Patient with Connective Tissue Disease. [PDF]
Brijawi O+5 more
europepmc +1 more source
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli+15 more
wiley +1 more source
Clinicopathological Features of Mixed Connective Tissue Disease-Related Myositis: A Case Series. [PDF]
Sakamoto N+4 more
europepmc +1 more source
IMMUNOLOGICAL STUDIES ON A C POLYSACCHARIDE COMPLEX OF GROUP A STREPTOCOCCI HAVING A DIRECT TOXIC EFFECT ON CONNECTIVE TISSUE [PDF]
John H. Schwab, William J. Cromartie
openalex +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source