Results 111 to 120 of about 542,433 (374)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Medical geography and its contribution to the aetiology of rare systemic connective tissue diseases : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Geography at Massey University [PDF]

, 1975
This thesis is in two interrelated parts. Part One traced the historical development of medical geography since the idea of applying a geographical perspective to medical problems was first mooted in 4 B.C.
Borman, Graham Barry
core  

Treatment of Connective Tissue Disease-Related Intractable Disease with Biological Therapeutics

Open Access Rheumatology: Research and Reviews, 2021
Yoshio Ozaki, Shosaku Nomura First Department of Internal Medicine, Kansai Medical University, Hirakata, JapanCorrespondence: Shosaku NomuraFirst Department of Internal Medicine, Kansai Medical University, 2-3-1 Shinmachi, Hirakata, Osaka, 573-1010 ...
Ozaki Y, Nomura S
doaj  

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, Volume 19, Issue 5, Page 1532-1545, May 2025.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

Роль дисплазії сполучної тканини в розвитку рецидиву генітального пролапсу [PDF]

, 2003
В статье приводится анализ данных, посвященных влиянию дисплазии соединительной ткани на развитие рецидива генитального пролапса. За период с 2003 по 2011 год было обследовано и прооперировано 600 гинекологических пациентов с признаками ...
Потапов, В.О., Банахевич, Р.М., Золотарьов, Д.Л., Акимова, К.Б., Єчин, А.В.   +4 more
core   +2 more sources

Pulmonary hypertension associated with connective tissue disease

Indian Journal of Rheumatology, 2017
Pulmonary hypertension (PH) is an important cause of morbidity and mortality in connective tissue diseases (CTDs). CTDs may cause PH due to several mechanisms; pulmonary arterial hypertension, associated interstitial lung disease, neuromuscular disease ...
Srinivas Rajagopala, Molly Mary Thabah
doaj   +1 more source

Plasma‐activated media selectively induces apoptotic death via an orchestrated oxidative stress pathway in high‐grade serous ovarian cancer cells

Molecular Oncology, Volume 19, Issue 4, Page 1170-1187, April 2025.
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies, Raja Ganesen, John Toubia, Sung‐Ha Hong, Sushil Kumar KC, Martin K. Oehler, Carmela Ricciardelli, Endre J. Szili, Nirmal Robinson, Melissa R. Pitman   +9 more
wiley   +1 more source

Mixed connective tissue disease: state of the art on clinical practice guidelines [PDF]

, 2018
Mixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies ...
Alexander, T, Amoura, Z, Avcin, T, Beretta, L, Bombardieri, S, Chaigne, B, Cutolo, M, Doria, A, Fischer-Betz, R., Fonseca, Je, Galetti, I, Guffroy, A, Guimar\ue3es, V, Hachulla, \uc9, Krieg, T, Launay, D, Lepri, G, M\ufcller-Ladner, U, Moinzadeh, P, Mosca, M, Rednic, S, Rodrigues, A, Schneider, M, Scir\ue8, Ca, Smith, V, Talarico, R, Tas, Sw, van Vollenhoven, Rf, Vieira, A   +28 more
core   +4 more sources

SKA1 promotes oncogenic properties in oral dysplasia and oral squamous cell carcinoma, and augments resistance to radiotherapy

Molecular Oncology, Volume 19, Issue 4, Page 1054-1074, April 2025.
The mitosis‐related gene SKA1 was among 629 genes consistently dysregulated in OSCC across nine public gene expression datasets. In OSCC cell lines, SKA1 promoted proliferation and migration, enhanced radioresistance, and reduced radiation‐induced senescence.
Alexander Michael Grandits, Barbara Andrea Reinoehl, Renate Wagner, Peter Kuess, Franziska Eckert, Anna Sophie Berghoff, Thorsten Fuereder, Rotraud Wieser   +7 more
wiley   +1 more source

A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia. [PDF]

, 2015
Inguinal hernia repair is one of the most commonly performed operations in the world, yet little is known about the genetic mechanisms that predispose individuals to develop inguinal hernias.
Ahituv, Nadav, Avins, Andrew, Chen, David C, Eckalbar, Walter L, Hinds, David, Jorgenson, Eric, Makki, Nadja, Shen, Ling, Tian, Chao   +8 more
core   +2 more sources