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Towards Early Diagnosis of Mixed Connective Tissue Disease: Updated Perspectives [PDF]

ImmunoTargets and Therapy, 2023
Chiara Alfia Ferrara,1 Gaetano La Rocca,2 Giuseppe Ielo,1 Alessandro Libra,1 Gianluca Sambataro1 1Department of Clinical and Experimental Medicine, Regional Referral Centre for Rare Lung Diseases, A.O.U.
Ferrara CA, La Rocca G, Ielo G, Libra A, Sambataro G   +4 more
doaj   +5 more sources

Mixed connective tissue disease.

Best Practice & Research Clinical Rheumatology, 2016
The concept of mixed connective tissue disease (MCTD) as a separate connective tissue disease (CTD) has persisted for more than four decades. High titers of antibodies targeting the U1 small nuclear ribonucleoprotein particle (U1 snRNP) in peripheral blood are a sine qua non for the diagnosis of MCTD, in addition to distinct clinical features including
R. Gunnarsson, S. Hetlevik, V. Lilleby, Ø. Molberg   +3 more
semanticscholar   +5 more sources

Interstitial Lung Disease in Mixed Connective Tissue Disease: An Advanced Search. [PDF]

Cureus, 2023
The spectrum of pulmonary manifestations associated with mixed connective tissue disease ranges from pulmonary hypertension and interstitial lung disease to pleural effusions, alveolar hemorrhage, and complications from the thromboembolic disease ...
Santacruz JC, Mantilla MJ, Rodriguez-Salas G, Rueda I, Pulido S, Varela DC, Londono J.   +6 more
europepmc   +2 more sources

Mixed connective tissue disease and severe renal disease – an apparent misconception? [PDF]

Rheumatology, 2022
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Filipe Oliveira Pinheiro, Pedro Madureira, Maria Seabra Rato, Lúcia Costa   +3 more
doaj   +2 more sources

Pulmonary thromboembolism as an atypical manifestation of mixed connective tissue disease in a young man: A case report [PDF]

Journal of International Medical Research
Mixed connective tissue disease is an autoimmune disorder characterized by the presence of various abnormal autoantibodies and systemic involvement. Similar to systemic lupus erythematosus, pulmonary manifestations commonly include interstitial fibrosis,
Chunchao Wang, Xinying Cui, Jingchun Jin
doaj   +2 more sources

Unravelling IPAF, VEDOSS and connective tissue diseases classifications through the mixed connective tissue disease spectrum [PDF]

RMD Open
Background Mixed connective tissue disease (MCTD) has long been debated as an early nonspecific phase/symptom of differentiated connective tissue diseases (dCTD), similarly to interstitial pneumonia with autoimmune features (IPAF) and very early ...
Patrice Cacoub, Eric Hachulla, Nathalie Costedoat-Chalumeau, Xavier Mariette, Olivier Lambotte, Luc Mouthon, Benjamin Chaigne, Thomas Hanslik, Christian Agard, Pascal Cohen, Bertrand Dunogue, Alexis Régent, Benjamin Terrier, Isabelle Kone-Paut, Maxime Samson, Bernard Bonnotte, Thomas Papo, Brigitte Bader-Meunier, Raphaele Seror, Hervé Levesque, Karim Sacre, Kevin Chevalier, Bertrand Godeau, Marc Michel, Ygal Benhamou, Veronique Le Guern, Jean Schmidt, Felix Ackermann, Jean-Emmanuel Kahn, Pierre Duhaut, Cécile Goujard, Benjamin Thoreau   +31 more
doaj   +2 more sources

Romosozumab‐Associated Recurrent Erythema Nodosum in Mixed Connective Tissue Disease [PDF]

ACR Open Rheumatology
Objective The aim of this study was to describe recurrent erythema nodosum (EN) temporally associated with romosozumab in a patient with mixed connective tissue disease and to examine the biologic plausibility of this association in the context of Wnt/β ...
Jose Luis Diaz Macip, Izabela Turcu, Jyothsna Goranti, Sreeja Sivaguru, Sai Priyanka Kodam, Zeeshan Afzal   +5 more
doaj   +2 more sources

Associations between nailfold capillaroscopy findings and interstitial lung disease in patients with mixed connective tissue disease

Archives of Medical Science, 2019
Introduction Mixed connective tissue disease (MCTD) is a chronic immune-mediated disorder defined by the combined presence of serum anti-RNP antibodies and distinct clinical features including progressive lung fibrosis.
Magdalena Celińska-Löwenhoff, Maciej Pastuszczak, Karolina Pełka, Magdalena Stec-Polak, Anna Wojas-Pelc, Jacek Musiał   +5 more
doaj   +2 more sources

Optical Coherence Tomography Angiography in Patients with Mixed Connective Tissue Disease [PDF]

Biomedicines
Background: Mixed connective tissue disease (MCTD) is a rare systemic autoimmune disease which presents with clinical features that overlap with at least two connective tissue disorders, including systemic lupus erythematosus (SLE), systemic sclerosis ...
Magdalena Szeretucha, Katarzyna Paczwa, Katarzyna Romanowska-Próchnicka, Sylwia Ornowska, Radosław Różycki, Joanna Gołębiewska   +5 more
doaj   +2 more sources

Mixed connective tissue disease

Современная ревматология, 2019
Mixed connective tissue disease (MCTD), also known as Sharp's syndrome, is a rare systemic connective tissue disorder that characterized by a combination of some features of systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis ...
R. U. Shayakhmetova, L. P. Ananyeva
doaj   +2 more sources