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Mixed Connective Tissue Disease. Results from a Nationwide Norwegian Cohort
, 2018 I sin avhandling «Mixed Connective Tissue Disease – Results from a Nationwide Norwegian Cohort» har lege og forsker Silje Reiseter og medarbeidere studert en gruppe pasienter med bindevevssykdommen Mixed Connective Tissue Disease (MCTD) i Norge ...
Reiseter, Silje
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Mixed connective tissue disease
, 2019 Mixed connective tissue disease (MCTD), also known as Sharp's syndrome, is a rare systemic connective tissue disorder that characterized by a combination of some features of systemic lupus erythematosus, systemic sclerosis, rheumatoid arthritis ...
L. P. Ananyeva, R. U. Shayakhmetova
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Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2017 Background The phenotypic stability of mixed connective tissue disease (MCTD) is not clear, and knowledge about disease activity and remission is scarce.
Aaløkken, Trond M +17 more
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CASE REPORT: MIXED CONNECTIVE TISSUE DISEASE (MCTD)
, 2022 Background:The term mixed connective tissue disease (MCTD) was coined by Sharp and colleagues in 1972 proving to that mixed connective tissue disease a systemic autoimmune disease which involves antibodies like anti-sm, Ro-52 recombinant, nucleosome,anti-
Hirni J Patel +5 more
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2016 Atherosclerosis is a chronic inflammatory disease of the arteries associated with various risk factors that promote lipid abnormalities, development and progression of atherosclerotic lesions, plaque rupture, and vascular thrombosis.
Marzena Olesińska +3 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Nitric oxide modulates expression of extracellular matrix genes linked to fibrosis in kidney mesangial cells [PDF]
, 2007 Mesangial cells are thought to be important mediators of glomerular inflammation and fibrosis. Studies have established a direct role for nitric oxide (NO) in the regulation of gene expression in mesangial cells.
Nelson, Peter J. +4 more
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