Results 11 to 20 of about 8,204,733 (251)

The enigma of mixed connective tissue disease—challenges in routine care [PDF]

, 2022
OBJECTIVES: As a rare and heterogeneous disease, mixed connective tissue disease (MCTD) represents a challenge. Herein, we aimed to unravel potential pitfalls including correct referral diagnosis, distinction from other connective tissue diseases (CTD ...
Britta Maurer, Alexandru Garaiman, Maurer, Britta, Garaiman, Alexandru, Jordan, Suzana, Wanzenried, Adrian, Distler, Oliver, Adrian Wanzenried, Suzana Jordan, Oliver Distler   +9 more
core   +2 more sources

Pulmonary thromboembolism as an atypical manifestation of mixed connective tissue disease in a young man: A case report. [PDF]

J Int Med Res
Mixed connective tissue disease is an autoimmune disorder characterized by the presence of various abnormal autoantibodies and systemic involvement. Similar to systemic lupus erythematosus, pulmonary manifestations commonly include interstitial fibrosis,
Wang C, Cui X, Jin J.
europepmc   +2 more sources

Interstitial Lung Disease in Patients with Mixed Connective Tissue Disease: A Retrospective Study. [PDF]

Int J Gen Med
Xueyan Shan,1,2 Yongpeng Ge3 1Department of Rheumatology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, People’s Republic of China; 2Postgraduate School, Beijing University of Chinese Medicine, Beijing, People’s Republic of ...
Shan X, Ge Y.
europepmc   +2 more sources

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]

, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R, Thomas Haberberger, Carol M. Black, Haberberger, T, Xu Shiwen, Martini, G, Holmes, A, Alan Holmes, Andrew Leask, Shiwen, X, David Abraham, Black, CM, Leask, A, Martin, GR, Abraham, D, George R. Martin, Richard Stratton, Giorgia Martini   +17 more
core   +1 more source

Review paper U1-RNP and TLR receptors in the pathogenesis of mixed connective tissue disease. Part I. The U1-RNP complex and its biological significance in the pathogenesis of mixed connective tissue disease

, 2015
Mixed connective tissue disease (MCTD) is a rare autoimmune syndrome, signified by complex interactions between disease-related phenomena, including inflammation, proliferative vascular arteriopathy, thrombotic events and humoral autoimmune processes. It
Agnieszka Paradowska-Gorycka
core   +1 more source

Juvenile mixed connective tissue disease: case series

, 2018
Mikst konnektif doku hastalığı birden fazla bağ doku hastalığına ait bulgular ile karakterize otoimmün bir hastalıktır. U1 RNP'ye karşı yüksek titre otoantikorlar ile karakterizedir. Hastaların %23'ünün çocukluk çağında bulgu verdiği bildirilmiştir.
Derya Ufuk Altıntaş, Sibel Balcı, Ekinci, Rabia Miray Kisla, Rabia Miray Ekinci Kışla, Mustafa Yılmaz, Altintas, Derya Ufuk, Balci, Sibel, Yilmaz, Mustafa, Rabia Miray Kışla Ekinci   +8 more
core   +2 more sources

Breast involvement in mixed connective tissue disease

, 2019
To date, mammographic involvement in mixed connective tissue disease has not been described in the literature to the authors’ knowledge. In addition, only 2 case reports have described panniculitis in mixed connective tissue disease. We present a patient
Ross Varma, MD, Manju Harshan, MD, Sandor Szilagyi, MD   +2 more
core   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Review papers U1-RNP and Toll-like receptors in the pathogenesis of mixed connective tissue disease Part II. Endosomal TLRs and their biological significance in the pathogenesis of mixed connective tissue disease

, 2015
Mixed connective tissue disease (MCTD) is a chronic autoimmune immunopathological disease of unknown etiology, which is characterized by the presence of various clinical symptoms and the presence of autoantibodies against U1-RNP particles.
Agnieszka Paradowska-Gorycka
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source