Results 41 to 50 of about 31,389 (264)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Is Sub-Epithelial Connective Tissue Graft Really a Gold Standard for the Treatment of Gingival Recession Defects?

Dental Hypotheses, 2011
Gingival recession defects are one of the most common peri-odontal problems. In the past few decades there have been several attempts to treat the gingival recession defects.
Ajay Mahajan, Ashu Bhardwaj, Poonam Mahajan   +2 more
doaj  

Clinical application of alternative materials for the treatment of gingival retraction with subepithelial connective tissue

口腔疾病防治, 2016
The gingival recession in the population has a high incidence, which leads to the root surface exposure, tooth sensitivity, and serious impact on the appearance.
ZHAO Jing, LI Xin-yue, SHI Dong
doaj   +1 more source

A new digital evaluation protocol applied in a retrospective analysis of periodontal plastic surgery of gingival recessions

Scientific Reports, 2021
This research aimed to develop a new digital evaluation protocol to objectively quantify the volumetric changes of root coverage periodontal plastic surgery when combined with connective tissue graft. Consecutive patients with Cairo recession type 1 (RT1)
Tiago Marques, N. M. Santos, Joana Fialho, J. Montero, A. Correia   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Full versus partial thickness flap to determine differentiation and over keratinization of non‐keratinized mucosa. A 3‐year split mouth randomized pilot study

Clinical and Experimental Dental Research, 2021
Objectives It was shown, that Connective Tissue Grafts (CTG) retrieved from the tuberosity tends to determine hyperplastic responses and may induce a beneficial over‐keratinization of non‐keratinized mucosa.
Algirdas Puisys, Viktorija Auzbikaviciute, Egle Vindasiute‐Narbute, Saulius Zukauskas, Dainius Razukevicus, Michel M. Dard   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effectiveness of Recombinant Human Bone Morphogenetic Protein‐2 in Socket Preservation: A Randomized Controlled Clinical and Sequential Human Histological Trial (BMP‐2 TRIAL)

Clinical and Experimental Dental Research
Objectives The aim of this study was to evaluate the effectiveness of recombinant human bone morphogenetic protein‐2 (rhBMP‐2) coated biphasic calcium phosphate (BCP) in socket preservation in comparison to BCP.
Saravanan Sampoornam Pape Reddy, Delfin Lovelina Francis, Harshini Thirumoorthi, Rahul, Manish Rathi, Harjeet Singh, Shaswata Karmakar, Shaili Pradhan   +7 more
doaj   +1 more source

Comparison of two techniques of harvesting connective tissue and its effects on healing pattern at palate and recession coverage at recipient site

Contemporary Clinical Dentistry, 2016
Aim: To compare the healing pattern in palate following harvestation of connective tissue graft by two different techniques and to compare the recession coverage at the recipient sites.
Nymphea Pandit, Meenakshi Khasa, Shalini Gugnani, Rajvir Malik, Deepika Bali   +4 more
doaj   +1 more source