Results 51 to 60 of about 31,389 (264)

The effect of different soft-tissue management techniques for alveolar ridge preservation: a randomized controlled clinical trial

International Journal of Implant Dentistry, 2021
Purpose For alveolar ridge preservation, various treatment protocols have been described. While most studies focus on the effect of the bone graft material, the aim of this study was to analyze the influence of different soft-tissue management techniques
Colline Papace, Christopher Büsch, Oliver Ristow, Martin Keweloh, Jürgen Hoffmann, Christian Mertens   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

What is the Outcome of Platelet-Rich Fibrin Therapy Compared to Connective Tissue Grafting When Treating Gingival Recession?

Dentistry Review
OBJECTIVES: To educate and inform patients about Research on PRF therapy and Connective Tissue Grafting, gingival recession treatment, and Platelet-Rich Fibrin therapy so they can make informed decisions about their needed gingival procedures.
Kelsea Collins, Quatesha Smith, Ashley Christman, RDH, BS   +2 more
doaj   +1 more source

Possibilities of modern procedures in gingival recession therapy [PDF]

Stomatološki glasnik Srbije, 2003
This study was designed to compare the effectiveness and predictability of GTR and connective tissue graft in the treatment of gingival recession. 15 recessions Miller class II and III were treated with bioabsorbable barrier and coronally advanced flap ...
Janković Saša, Dimitrijević Božidar
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Effects of Subepithelial Connective Tissue Graft for Root Coverage. Subepithelial Connective Tissue Treatment.

Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology), 1998
歯肉退縮による審美障害を主訴として来院した患者10名 (男性3名, 女性7名) の42部位を対象に, 上皮下結合組織移植術により根面被覆を行った。術前に, 退縮の深さおよび幅, アタッチメントレベル, 角化歯肉の幅の臨床診査を行った。臨床所見ならびに術後6カ月の臨床パラメーターの推移を統計学的に検索した。また, 上皮下結合組織移植術後の治癒形態を知る目的でイヌを用い, 下顎左右第2, 3, 4前臼歯部に上皮下結合組織移植術, または遊離歯肉移植術を行い病理組織学的に観察し, 以下の結論を得た。1) 露出根面の被覆率 (術前のVR一術後のVR) /術前のVR×100 (%) は, 全体で73.95±32.27%であった。2) 歯種別では, 上顎が下顎に比べて有意に高い根面被覆率を示した。また ...
Matsumura, Akiko, Konobu, Hiroyuki, Nakaya, Hiroshi, Kamoi, Kyuichi   +3 more
openaire   +3 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Lateral pedicle graft for repair of residual gingival defect following complete surgical excision of a pyogenic granuloma

Journal of International Clinical Dental Research Organization, 2016
The pyogenic granuloma, one of the gingival lesions, has recurrence rate of 16%. To minimize the recurrence rate, it must be completely excised. Complete surgical excision can result in residual gingival defect.
Awadhesh Kumar Singh, Abhisek Gautam
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source