Results 51 to 60 of about 1,981,327 (296)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Uncovering of transplanted connective tissue graft: Clinical and histological evaluation. [PDF]

Clin Adv Periodontics
BackgroundPeriodontal plastic surgery aims to restore recessions and dehiscence around teeth and implants. Several techniques, such as subepithelial connective tissue graft (CTG), were proposed with the main outcome of improving volume and root coverage.
Fratini A, Mancini L, Liguori MG, Gotti S, Marchetti E.   +4 more
europepmc   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Is Sub-Epithelial Connective Tissue Graft Really a Gold Standard for the Treatment of Gingival Recession Defects?

Dental Hypotheses, 2011
Gingival recession defects are one of the most common peri-odontal problems. In the past few decades there have been several attempts to treat the gingival recession defects.
Ajay Mahajan, Ashu Bhardwaj, Poonam Mahajan   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Clinical application of alternative materials for the treatment of gingival retraction with subepithelial connective tissue

口腔疾病防治, 2016
The gingival recession in the population has a high incidence, which leads to the root surface exposure, tooth sensitivity, and serious impact on the appearance.
ZHAO Jing, LI Xin-yue, SHI Dong
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Coronally advanced flap with and without connective tissue graft in root coverage procedure: A Case Series

Objective: This paper aims to report the outcome of the coronally advanced flap with and without connective tissue graft in the root coverage procedure.
Situmorang, Desy, Ervina, Irma, Amalia, Martina, Budi,   +3 more
core   +3 more sources

A new digital evaluation protocol applied in a retrospective analysis of periodontal plastic surgery of gingival recessions

Scientific Reports, 2021
This research aimed to develop a new digital evaluation protocol to objectively quantify the volumetric changes of root coverage periodontal plastic surgery when combined with connective tissue graft. Consecutive patients with Cairo recession type 1 (RT1)
Tiago Marques, N. M. Santos, Joana Fialho, J. Montero, A. Correia   +4 more
doaj   +1 more source