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Human connectomics [PDF]

Current Opinion in Neurobiology, 2011
Recent advances in non-invasive neuroimaging have enabled the measurement of connections between distant regions in the living human brain, thus opening up a new field of research: Human connectomics. Different imaging modalities allow the mapping of structural connections (axonal fibre tracts) as well as functional connections (correlations in time ...
Timothy E.J. Behrens, Olaf Sporns
openalex   +3 more sources

NeuroGraph: Benchmarks for Graph Machine Learning in Brain Connectomics [PDF]

Neural Information Processing Systems, 2023
Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional magnetic resonance
Anwar Said, Roza G. Bayrak, Tyler Derr, Mudassir Shabbir, Daniel Moyer, Catie Chang, X. Koutsoukos   +6 more
semanticscholar   +1 more source

Comparative Connectomics [PDF]

Trends in Cognitive Sciences, 2016
We introduce comparative connectomics, the quantitative study of cross-species commonalities and variations in brain network topology that aims to discover general principles of network architecture of nervous systems and the identification of species-specific features of brain connectivity. By comparing connectomes derived from simple to more advanced
van den Heuvel, Martijn P, Bullmore, Edward T, Sporns, Olaf   +2 more
openaire   +5 more sources

The topographic connectome [PDF]

Current Opinion in Neurobiology, 2013
Central to macro-connectomics and much of systems neuroscience is the idea that we can summarise macroscopic brain connectivity using a network of 'nodes' and 'edges'--functionally distinct brain regions and the connections between them. This is an approach that allows a deep understanding of brain dynamics and how they relate to brain circuitry.
Timothy E.J. Behrens, Timothy E.J. Behrens, Saad Jbabdi, Stamatios N. Sotiropoulos   +3 more
openaire   +6 more sources

Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Open questions remain regarding the optimal target, or sweetspot, for deep brain stimulation (DBS) in, for example, Parkinson's disease. Previous studies introduced different methods of mapping DBS effects to determine sweetspots. While having a direct impact on surgical targeting and postoperative programming in DBS, these methods ...
Till A. Dembek, Juan Carlos Baldermann, Jan‐Niklas Petry‐Schmelzer, Hannah Jergas, Harald Treuer, Veerle Visser‐Vandewalle, Haidar S. Dafsari, Michael T. Barbe   +7 more
wiley   +1 more source

Functional connectomics reveals general wiring rule in mouse visual cortex

bioRxiv, 2023
Understanding the relationship between circuit connectivity and function is crucial for uncovering how the brain implements computation. In the mouse primary visual cortex (V1), excitatory neurons with similar response properties are more likely to be ...
Zhuokun Ding, Paul G. Fahey, S. Papadopoulos, Eric Y. Wang, Brendan Celii, Christos Papadopoulos, Alex Kunin, Andersen Chang, Jiakun Fu, Zhiwei Ding, Saumil S. Patel, Kayla Ponder, J. A. Bae, A. Bodor, D. Brittain, J. Buchanan, D. Bumbarger, M. Castro, Erick Cobos, S. Dorkenwald, L. Elabbady, A. Halageri, Z. Jia, C. Jordan, D. Kapner, N. Kemnitz, S. Kinn, Kisuk Lee, Kai Li, R. Lu, T. Macrina, G. Mahalingam, E. Mitchell, S. S. Mondal, S. Mu, Barak Nehoran, S. Popovych, C. Schneider-Mizell, W. Silversmith, Marc M. Takeno, R. Torres, N. Turner, W. Wong, Jingpeng Wu, W. Yin, Szi-chieh Yu, E. Froudarakis, Fabian H Sinz, H. Seung, F. Collman, N. D. da Costa, R. Reid, Edgar Y. Walker, X. Pitkow, Jacob Reimer, A. Tolias   +55 more
semanticscholar   +1 more source

Visualization in Connectomics [PDF]

, 2014
Connectomics is a field of neuroscience that analyzes neuronal connections. A connectome is a complete map of a neuronal system, comprising all neuronal connections between its structures. The term "connectome" is close to the word "genome" and implies completeness of all neuronal connections, in the same way as a genome is a complete listing of all ...
Jos B. T. M. Roerdink, Stefan Bruckner, Verena Kaynig, Charl P. Botha, Vincent J. Dercksen, Hanspeter Pfister, Hans-Christian Hege   +6 more
openaire   +2 more sources

High-contrast en bloc staining of mouse whole-brain and human brain samples for EM-based connectomics

Nature Methods, 2023
Connectomes of human cortical gray matter require high-contrast homogeneously stained samples sized at least 2 mm on a side, and a mouse whole-brain connectome requires samples sized at least 5–10 mm on a side.
Kun Song, Zhihui Feng, M. Helmstaedter
semanticscholar   +1 more source

BrainNet Viewer: A Network Visualization Tool for Human Brain Connectomics

PLoS ONE, 2013
The human brain is a complex system whose topological organization can be represented using connectomics. Recent studies have shown that human connectomes can be constructed using various neuroimaging technologies and further characterized using ...
Mingrui Xia, Jinhui Wang, Yong He
semanticscholar   +1 more source

Higher-order connectomics of human brain function reveals local topological signatures of task decoding, individual identification, and behavior

bioRxiv, 2023
Traditional models of human brain activity often represent it as a network of pairwise interactions between brain regions. Going beyond this limitation, recent approaches have been proposed to infer higher-order interactions from temporal brain signals ...
Andrea Santoro, F. Battiston, Maxime Lucas, Giovanni Petri, Enrico Amico   +4 more
semanticscholar   +1 more source