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Brain connectomics: time for a molecular imaging perspective?
Trends in Cognitive Sciences, 2023 In the past two decades brain connectomics has evolved into a major concept in neuroscience. However, the current perspective on brain connectivity and how it underpins brain function relies mainly on the hemodynamic signal of functional magnetic ...
Arianna Sala +10 more
semanticscholar +1 more source
Connectomics and epilepsy [PDF]
Current Opinion in Neurology, 2013 Tremendous advances have occurred in recent years in elucidating basic mechanisms of epilepsy at the level of ion channels and neurotransmitters. Epilepsy, however, is ultimately a disease of functionally and/or structurally aberrant connections between neurons and groups of neurons at the systems level.
Jerome Engel +6 more
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Place cell maps slowly develop via competitive learning and conjunctive coding in the dentate gyrus
Nature Communications, 2020 Place cells in the hippocampus fire action potentials at spatially selective firing fields that collectively map the environments. Here, the authors show how these activity patterns develop with experience in mice and determine the importance of ...
Soyoun Kim +2 more
doaj +1 more source
Future Directions for Chemosensory Connectomes: Best Practices and Specific Challenges
Frontiers in Systems Neuroscience, 2022 Ecological chemosensory stimuli almost always evoke responses in more than one sensory system. Moreover, any sensory processing takes place along a hierarchy of brain regions.
Maria G. Veldhuizen +12 more
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BrainNet Viewer: A Network Visualization Tool for Human Brain Connectomics
PLoS ONE, 2013 The human brain is a complex system whose topological organization can be represented using connectomics. Recent studies have shown that human connectomes can be constructed using various neuroimaging technologies and further characterized using ...
Mingrui Xia, Jinhui Wang, Yong He
semanticscholar +1 more source
, 2021 Neuromodulation: Technology at the Neural Interface, EarlyView.
Tim A. M. Bouwens van der Vlis +1 more
wiley +1 more source
Genetics of the connectome [PDF]
NeuroImage, 2013 Connectome genetics attempts to discover how genetic factors affect brain connectivity. Here we review a variety of genetic analysis methods--such as genome-wide association studies (GWAS), linkage and candidate gene studies--that have been fruitfully adapted to imaging data to implicate specific variants in the genome for brain-related traits. Studies
Paul M. Thompson +4 more
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Expanding connectomics to the laminar level: A perspective
Network Neuroscience, 2023 Despite great progress in uncovering the complex connectivity patterns of the human brain over the last two decades, the field of connectomics still experiences a bias in its viewpoint of the cerebral cortex.
Ittai Shamir, Yaniv Assaf
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Connectomic approaches before the connectome
NeuroImage, 2013 Connectome is a term with a short history but a long past. Since the origins of neuroscience the concept of a 'map of neural connections' has been a constant inspiring idea for those who believed the brain as the organ of intellect. A myriad of proto-connectome maps have been produced throughout the centuries, each one reflecting the theory and method ...
Marco Catani +3 more
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Connecting Connectomes to Physiology
The Journal of Neuroscience, 2023 With the advent of volumetric EM techniques, large connectomic datasets are being created, providing neuroscience researchers with knowledge about the full connectivity of neural circuits under study. This allows for numerical simulation of detailed, biophysical models of each neuron participating in the circuit. However, these models typically include
Alexander Borst, Christian Leibold
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