Results 31 to 40 of about 16,090 (228)
A Pipeline for Volume Electron Microscopy of the Caenorhabditis elegans Nervous System. [PDF]
, 2018 The "connectome," a comprehensive wiring diagram of synaptic connectivity, is achieved through volume electron microscopy (vEM) analysis of an entire nervous system and all associated non-neuronal tissues. White et al.
Chisholm, Andrew D +7 more
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Current Opinion in Neurobiology, 2018 Brain cells communicate with one another via local and long-range synaptic connections. Structural connectivity is the foundation for neural function. Brain-wide connectivity can be described at macroscopic, mesoscopic and microscopic levels. The mesoscale connectome represents connections between neuronal types across different brain regions. Building
openaire +2 more sources
A Case Study in Connectomics: The History, Mapping, and Connectivity of the Claustrum
Frontiers in Neuroinformatics, 2014 The claustrum seems to have been waiting for the science of connectomics. Due to its tiny size, the structure has remained remarkably difficult to study until modern technological and mathematical advancements like graph theory, connectomics, diffusion ...
Carinna Margaret Torgerson +1 more
doaj +1 more source
Whole-brain estimates of directed connectivity for human connectomics
NeuroImage, 2021 Connectomics is essential for understanding large-scale brain networks but requires that individual connection estimates are neurobiologically interpretable. In particular, a principle of brain organization is that reciprocal connections between cortical
Stefan Frässle +5 more
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Mapping hybrid functional-structural connectivity traits in the human connectome [PDF]
, 2018 One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open problem that ...
Amico, Enrico, Goñi, Joaquín
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Micro-drive and headgear for chronic implant and recovery of optoelectronic probes
Scientific Reports, 2017 Silicon probes are multisite electrodes used for the electrophysiological recording of large neuronal ensembles. Optoelectronic probes (OEPs) are recent upgrades that allow, in parallel, the delivery of local optical stimuli.
Jinho Chung +4 more
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Scientific Reports, 2018 A bright, red-shifted Genetically Encoded Voltage Indicator (GEVI) was developed using a modified version of the fluorescent protein, tdTomato. Dimerization of the fluorescent domain for ArcLight-type GEVIs has been shown to affect the signal size of the
Bumjun Yi +4 more
doaj +1 more source
SynEM, automated synapse detection for connectomics
eLife, 2017 Nerve tissue contains a high density of chemical synapses, about 1 per µm3 in the mammalian cerebral cortex. Thus, even for small blocks of nerve tissue, dense connectomic mapping requires the identification of millions to billions of synapses. While the
Benedikt Staffler +5 more
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NeuroImage, 2022 Localising accurate brain regions needs careful evaluation in each experimental species due to their individual variability. However, the function and connectivity of brain areas is commonly studied using a single-subject cranial landmark-based ...
Takayuki Ose +16 more
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Navigation of brain networks [PDF]
, 2018 Understanding the mechanisms of neural communication in large-scale brain networks remains a major goal in neuroscience. We investigated whether navigation is a parsimonious routing model for connectomics. Navigating a network involves progressing to the
Heuvel, Martijn P. van den +2 more
core +4 more sources