Results 41 to 50 of about 8,362 (210)

FlyWire: Online community for whole-brain connectomics

Nature Methods, 2020
Due to advances in automated image acquisition and analysis, whole-brain connectomes with 100,000 or more neurons are on the horizon. Proofreading of whole-brain automated reconstructions will require many person-years of effort, due to the huge volumes ...
Sven Dorkenwald, Claire E. McKellar, T. Macrina, N. Kemnitz, Kisuk Lee, R. Lu, Jingpeng Wu, S. Popovych, E. Mitchell, Barak Nehoran, Z. Jia, J. A. Bae, S. Mu, Dodam Ih, M. Castro, Oluwaseun Ogedengbe, A. Halageri, Zoe Ashwood, J. Zung, D. Brittain, F. Collman, C. Schneider-Mizell, C. Jordan, W. Silversmith, Christa A. Baker, David S. Deutsch, Lucas Encarnacion-Rivera, Sandeep Kumar, A. Burke, Jay Gager, James Hebditch, Selden Koolman, Merlin Moore, Sarah Morejohn, B. Silverman, K. Willie, Ryan Willie, Szi-chieh Yu, Mala Murthy, H. Seung   +39 more
semanticscholar   +1 more source

neuPrint: An open access tool for EM connectomics

Frontiers in Neuroinformatics, 2022
Due to advances in electron microscopy and deep learning, it is now practical to reconstruct a connectome, a description of neurons and the chemical synapses between them, for significant volumes of neural tissue.
Stephen M. Plaza, Jody Clements, Tom Dolafi, L. Umayam, Nicole N. Neubarth, Louis K. Scheffer, S. Berg   +6 more
semanticscholar   +1 more source

BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets

Communications Biology, 2019
Understanding how cognitive functions emerge from brain structure depends on quantifying how discrete regions are integrated within the broader cortical landscape.
Reinder Vos de Wael, O. Benkarim, C. Paquola, S. Larivière, J. Royer, Shahin Tavakol, Ting Xu, Seokjun Hong, S. Valk, B. Mišić, M. Milham, D. Margulies, J. Smallwood, B. Bernhardt   +13 more
semanticscholar   +1 more source

A Convergent Pathway for Stimulation‐Induced Dyskinesia Following Deep Brain Stimulation

Movement Disorders, EarlyView.
Abstract Background Stimulation‐induced dyskinesias (SID) from deep brain stimulation (DBS) of the subthalamic nucleus (STN) and globus pallidus internus (GPi) are uncommon; however, they are increasingly recognized. Once considered transient and indicative of effective neuromodulation, SID are now seen as potential therapy‐limiting side effects, akin ...
Joshua K. Wong, Andreas Horn, Erik H. Middlebrooks, Matthew R. Burns, Michael S. Okun   +4 more
wiley   +1 more source

A Survey of Visualization and Analysis in High‐Resolution Connectomics

Computer graphics forum (Print), 2022
The field of connectomics aims to reconstruct the wiring diagram of Neurons and synapses to enable new insights into the workings of the brain. Reconstructing and analyzing the Neuronal connectivity, however, relies on many individual steps, starting ...
Johanna Beyer, J. Troidl, S. Boorboor, Markus Hadwiger, A. Kaufman, Hanspeter Pfister   +5 more
semanticscholar   +1 more source

Brain Networks Route Neurodegeneration Patterns in Patients with Progressive Supranuclear Palsy

Movement Disorders, EarlyView.
Abstract Background Progressive supranuclear palsy (PSP) is a neurodegenerative disease driven by 4‐repeat τ pathology, which is thought to propagate across interconnected neurons. Objectives We hypothesized that interconnected brain regions exhibit correlated atrophy, and that atrophy propagates network‐like from fast‐declining epicenters to connected
Carla Palleis, Andrea Quattrone, Amir Dehsarvi, Sebastian N. Roemer‐Cassiano, Alexander M. Bernhardt, The AL‐108‐231 Investigators, the PASSPORT Study Group, Ikuko Aiba, Angelo Antonini, Diana Apetauerova, Jean‐Philippe Azulay, Ernest Balaguer Martinez, Jee Bang, Paolo Barone, Matthew Barrett, Danny Bega, Daniela Berg, Koldo Berganzo Corrales, Yvette Bordelon, Adam L Boxer, Moritz Brandt, Norbert Brueggemann, Giovanni Castelnovo, Roberto Ceravolo, Rosalind Chuang, Sun Ju Chung, Alistair Church, Jean‐Christophe Corvol, Paola Cudia, Marian Dale, Luc Defebvre, Sophie Drapier, Erika D Driver‐Dunckley, Georg Ebersbach, Karla M Eggert, Aaron Ellenbogen, Alexandre Eusebio, Andrew H Evans, Natalia Fedorova, Elizabeth Finger, Alexandra Foubert‐Samier, Boyd Ghosh, Lawrence Golbe, Francisco Grandas Perez, Murray Grossman, Deborah Hall, Kyoko Hamada, Kazuko Hasegawa, Guenter Hoeglinger, Lawrence Honig, David Houghton, Xuemei Huang, Stuart Isaacson, Jaime Kulisevsky Bojarski, Anthony E. Lang, Peter Nigel Leigh, Biomedical Research, Irene Litvan, Juan Jose Lopez Lozano, Jose Luis Lopez‐Sendon Moreno, Albert Christian Ludolph, Ma Rosario Luquin Piudo, Irene Martinez Torres, Nikolaus McFarland, Wassilios Meissner, Tiago Mestre, Pablo Mir Rivera, Eric Molho, Britt Mollenhauer, Huw R Morris, Miho Murata, Tomokazu Obi, Fabienne Ory Magne, Padraig O'Suilleabhain, Rajesh Pahwa, Alexander Pantelyat, Nicola Pavese, Dmitry Pokhabov, Johannes Prudlo, Federico Rodriguez‐Porcel, James Rowe, Joseph Savitt, Alfons Schnitzler, Joerg B Schulz, Klaus Seppi, Binit Shah, Holly Shill, David Shprecher, Maria Stamelou, Malcolm Steiger, Yuji Takahashi, Hiroshi Takigawa, Carmela Tartaglia, Lars Toenges, Kardiologische Studienambulanz, Daniel Truong, Winona Tse, Paul Tuite, Dieter Volc, Anne‐Marie A Wills, Dirk Woitalla, Tao Xie, Tatsuhiko Yuasa, Sarah Elizabeth Zauber, Theresa Zesiewicz, David Williams, Anne Louise Lafontaine, Connie Marras, Mandar Jog, Michael Panisset, Anthony Lang, Lesley Parker, Alistair J. Stewart, Jean‐Christophe Corvol, Jean‐Philippe Azulay, Philippe Couratier, Brit Mollenhauer, Stefan Lorenzl, Albert Ludolph, Reiner Benecke, Günter Höglinger, Axel Lipp, Heinz Reichmann, Dirk Woitalla, Dennis Chan, Adam Zermansky, David Burn, Andrew Lees, Adam Boxer, Bruce L. Miller, Iryna V. Lobach, Erik Roberson, Lawrence Honig, Edward Zamrini, Rajesh Pahwa, Yvette Bor‐delon, Erika Driver‐Dunkley, Stephanie Lessig, Mark Lew, Kyle Womack, Brad Boeve, Joseph Ferrara, Argyle Hillis, Daniel Kaufer, Rajeev Kumar, Tao Xie, Steven Gunzler, Theresa Zesiewicz, Praveen Dayalu, Lawrence Golbe, Murray Grossman, Joseph Jancovic, Scott McGinnis, Anthony Santiago, Paul Tuite, Stuart Isaacson, Julie Leegwater‐Kim, Irene Litvan, Murray Grossman, David S. Knopman, Bruce L. Miller, Lon S. Schneider, Rachelle S. Doody, Lawrence I. Golbe, Erik D. Roberson, Mary Koestler, Clifford R. Jack, Viviana Van Deerlin, Christopher Randolph, Iryna V. Lobach, Illana Gozes, Steve Whitaker, Joe Hirman, Michael Gold, Bruce H. Morimoto, Hans‐Jürgen Huppertz, Maura Malpetti, Adam L. Boxer, Johannes Gnörich, Lukas Frontzkowski, Johannes Levin, Matthias Brendel, Günter U. Höglinger, Nicolai Franzmeier   +183 more
wiley   +1 more source

Disruption of mitochondria–sarcoplasmic reticulum microdomain connectomics contributes to sinus node dysfunction in heart failure

Proceedings of the National Academy of Sciences of the United States of America, 2022
Significance The human heart beats 60 to 80 times a minute, which can amount to more than 3 billion heartbeats in one’s lifetime. Each heartbeat is initiated by the sinoatrial node (SAN). SAN dysfunction is a common feature of heart failure (HF). However,
Lu Ren, R. Gopireddy, G. Perkins, Hao Zhang, V. Timofeyev, Y. Lyu, Daphne A Diloretto, Pauline Trinh, Padmini Sirish, James L Overton, Wilson Xu, N. Grainger, Y. Xiang, E. Dedkova, Xiao-Dong Zhang, E. Yamoah, Manuel F. Navedo, Phung N. Thai, N. Chiamvimonvat   +18 more
semanticscholar   +1 more source

Visualizing the human connectome

NeuroImage, 2013
Innovations in data visualization punctuate the landmark advances in human connectome research since its beginnings. From tensor glyphs for diffusion-weighted imaging, to advanced rendering of anatomical tracts, to more recent graph-based representations of functional connectivity data, many of the ways we have come to understand the human connectome ...
Margulies, D., Böttger, J., Watanabe, A., Gorgolewski, K.   +3 more
openaire   +4 more sources

Cross‐site harmonization of diffusion MRI data without matched training subjects

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose Diffusion MRI (dMRI) data typically suffer of significant cross‐site variability, which prevents naively performing pooled analyses. To attenuate cross‐site variability, harmonization methods such as the rotational invariant spherical harmonics (RISH) have been introduced to harmonize the dMRI data at the signal level.
Alberto De Luca, Tine Swartenbroekx, Harro Seelaar, John van Swieten, Suheyla Cetin Karayumak, Yogesh Rathi, Ofer Pasternak, Lize Jiskoot, Alexander Leemans   +8 more
wiley   +1 more source

Comparative Primate Connectomics

Brain, Behavior and Evolution, 2018
A connectome is a comprehensive map of neural connections of a species nervous system. While recent work has begun comparing connectomes across a wide breadth of species, we present here a more detailed and specific comparison of connectomes across the primate order.
Rilling, James K., van den Heuvel, Martijn P.   +1 more
openaire   +5 more sources