Results 71 to 80 of about 16,090 (228)

Functional Connectivity to the Cerebellum and Resting‐State Networks Predict Earlier Improvement of Dystonia Following Globus Pallidus Internus‐Deep Brain Stimulation (GPi‐DBS)

Movement Disorders, EarlyView.
Early improvement of dystonia after globus pallidus internus‐deep brain stimulation (GPi‐DBS) is associated with stimulation of the globus pallidus externus‐subthalamic nucleus (GPe‐STN) fibers and the lenticular fasciculus. Functional connectivity to the cerebellar cortex and the limbic and default mode networks predict early improvement of symptoms ...
A. Enrique Martinez‐Nunez, Vyshak Chandra, Chance R. Fleeting, Aashay Patel, Kelly D. Foote, Justin D. Hilliard, Marta San Luciano Palenzuela, Coralie de Hemptinne, Michael S. Okun, Joshua K. Wong   +9 more
wiley   +1 more source

Selective vulnerability of parvocellular oxytocin neurons in social dysfunction

Nature Communications
Selective vulnerability offers a conceptual framework for understanding neurodegenerative disorders such as Parkinson’s disease, where specific neuronal types are selectively affected and adjacent ones are spared.
Masafumi Tsurutani, Teppei Goto, Mitsue Hagihara, Satsuki Irie, Kazunari Miyamichi   +4 more
doaj   +1 more source

Distinct tumor signatures using deep learning-based characterization of the peritumoral microenvironment in glioblastomas and brain metastases

Scientific Reports, 2021
Tumor types are classically distinguished based on biopsies of the tumor itself, as well as a radiological interpretation using diverse MRI modalities.
Zahra Riahi Samani, Drew Parker, Ronald Wolf, Wes Hodges, Steven Brem, Ragini Verma   +5 more
doaj   +1 more source

Cartography and Connectomes [PDF]

Neuron, 2013
The past 25 years have seen great progress in parcellating the cerebral cortex into a mosaic of many distinct areas in mice, monkeys, and humans. Quantitative studies of interareal connectivity have revealed unexpectedly many pathways and a wide range of connection strengths in mouse and macaque cortex. In humans, advances in analyzing "structural" and
openaire   +2 more sources

Monoaminergic Networks of Cognitive and Behavioral Symptoms in Early Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is associated with several behavioral and cognitive symptoms, the neurobiological background of which is not yet fully understood. Objectives The aim was to investigate the association between monoamine function and four specific nonmotor symptoms in early PD using the Parkinson's Progression Markers ...
Kalle J. Niemi, Valtteri Kaasinen, Rimona S. Weil, Juho Joutsa   +3 more
wiley   +1 more source

Ontology-based approach for in vivo human connectomics: the medial Brodmann area 6 case study

Frontiers in Neuroinformatics, 2015
Different non-invasive neuroimaging modalities and multi-level analysis of human connectomics datasets yield a great amount of heterogeneous data which are hard to integrate into an unified representation.
Tristan eMoreau, Bernard eGibaud
doaj   +1 more source

Automated Synapse Detection Method for Cerebellar Connectomics

Frontiers in Neuroanatomy, 2022
The connectomic analyses of large-scale volumetric electron microscope (EM) images enable the discovery of hidden neural connectivity. While the technologies for neuronal reconstruction of EM images are under rapid progress, the technologies for synapse ...
Changjoo Park, Changjoo Park, Changjoo Park, Jawon Gim, Jawon Gim, Sungjin Lee, Kea Joo Lee, Jinseop S. Kim, Jinseop S. Kim   +8 more
doaj   +1 more source

Aberrant posterior cingulate connectivity classify first-episode schizophrenia from controls: A machine learning study

, 2020
Background Posterior cingulate cortex (PCC) is a key aspect of the default mode network (DMN). Aberrant PCC functional connectivity (FC) is implicated in schizophrenia, but the potential for PCC related changes as biological classifier of schizophrenia ...
Deng, W., Greenshaw, A., Guo, W., Kong, X., Li, M., Li, T., Li, X., Li, X., Liang, S., Ma, X., Meng, Y., Wang, Q., Yu, H., Zhang, C., Zhao, L.   +14 more
core   +1 more source

Do we agree on seizure reduction after vagus nerve stimulation? Interrater reliability of retrospective and prospective seizure frequency ratings from the CONNECTiVOS database

Epilepsia, EarlyView.
Abstract Objective Although vagus nerve stimulation (VNS) is a well‐established neuromodulation therapy for drug‐resistant epilepsy, treatment outcomes remain heterogeneous. One possible source of variability lies in differing interpretations of seizure frequency ratings (SFRs).
Thiemo F. Dinger, Karim Mithani, Hosni Abu Al‐Hasan, Leeor Yefet, Farbod Niazi, Hrishikesh Suresh, Simeon M. Wong, Venethia Danthine, Alexandre Berger, Ivanna Yau, Lyndsey McRae, James T. Rutka, Eisha A. Christian, Shelly Weiss, Lauren Sham, Elizabeth Donner, Vann Chau, Hanan Al‐Johani, Flavio Leao Lima, Arjun Chandran, Ramazan Jabbarli, Ulrich Sure, Aristides Hadjinicolaou, Philippe Major, Alexander G. Weil, Jignesh Tailor, Taylor J. Abel, Madison Remick, Emefa Akwayena, Dewi Schrader, Robert J. Bollo, Matthew D. Smyth, Diane Aum, Sean Lew, Shelly Wang, Toba Niazi, Jeffrey S. Raskin, Elysa Widjaja, Howard L. Weiner, Nisha Gadgil, Melissa A. LoPresti, Aria Fallah, Elizabeth Kerr, Puneet Jain, George M. Ibrahim   +44 more
wiley   +1 more source

Reconstructing neural circuits using multiresolution correlated light and electron microscopy

Frontiers in Neural Circuits, 2022
Correlated light and electron microscopy (CLEM) can be used to combine functional and molecular characterizations of neurons with detailed anatomical maps of their synaptic organization.
Karl Friedrichsen, Karl Friedrichsen, Karl Friedrichsen, Pratyush Ramakrishna, Pratyush Ramakrishna, Pratyush Ramakrishna, Jen-Chun Hsiang, Jen-Chun Hsiang, Jen-Chun Hsiang, Katia Valkova, Katia Valkova, Katia Valkova, Daniel Kerschensteiner, Daniel Kerschensteiner, Daniel Kerschensteiner, Josh L. Morgan, Josh L. Morgan, Josh L. Morgan   +17 more
doaj   +1 more source