Results 81 to 90 of about 6,029 (179)

Connectome Classification: Statistical Connectomics for Analysis of Connectome Data

, 2014
Slides for talk I gave at Duke University on April 2011.
openaire   +1 more source

Segmentation fusion for connectomics [PDF]

2011 International Conference on Computer Vision, 2011
We address the problem of automatic 3D segmentation of a stack of electron microscopy sections of brain tissue. Unlike previous efforts, where the reconstruction is usually done on a section-to-section basis, or by the agglomerative clustering of 2D segments, we leverage information from the entire volume to obtain a globally optimal 3D segmentation ...
Amelio Vázquez Reina, Michael Gelbart, Daniel Huang 0001, Jeff Lichtman, Eric L. Miller 0001, Hanspeter Pfister   +5 more
openaire   +2 more sources

Human brain connectome profiles mediate the relationship between pathology burden and clinical phenotypes in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Mild cognitive impairment (MCI), a prodromal stage of Alzheimer's disease (AD), shows pronounced clinical heterogeneity poorly explained by pathology burden, representing a gap complicating prognosis. As the brain operates as a complex network for information integration, we hypothesized that connectome architecture mediates the ...
Yating Li, Dong Wang, Rongshen Zhou, Shaozhen Yan, Dawei Wang, Yongbin Wei, Hongxiang Yao, Bo Zhou, Jie Lu, Pan Wang, Zhengluan Liao, Ying Han, Xi Zhang, Yihe Zhang, Yong Liu, Kun Zhao, for the Alzheimer's Disease Neuroimaging Initiative   +16 more
wiley   +1 more source

Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease

Annals of Neurology, Volume 100, Issue 1, Page 22-35, July 2026.
Objective Accurate electrode placement and individual stimulation parameters influence the outcomes of subthalamic deep brain stimulation in Parkinson's disease. Neuroimaging‐based models can help evaluate how electrode placement impacts improvement, aiming to reduce the burden of programming.
Patricia Zvarova, Christina van der Linden, Ningfei Li, Konstantin Butenko, Thea Berger, Garance M. Meyer, Ilkem Aysu Sahin, Lukas L. Goede, Bahne H. Bahners, Barbara Hollunder, Till A. Dembek, Andrew R. Pines, Martin Reich, Jens Volkmann, Vincent J. J. Odekerken, Rob M. A. de Bie, Xin Xu, Zhipei Ling, Chen Yao, Andrea A. Kühn, Surjo R. Soekadar, Kerstin Ritter, Michael T. Barbe, Veerle Visser‐Vandewalle, Michael D. Fox, Jan Niklas Petry‐Schmelzer, Nanditha Rajamani, Andreas Horn   +27 more
wiley   +1 more source

Golgi: interactive online brain mapping

Frontiers in Neuroinformatics, 2015
Golgi (http://www.usegolgi.com) is a prototype interactive brain map of the rat brain that helps researchers intuitively interact with neuroanatomy, connectomics, and cellular and chemical architecture.
Ramsay Alexander Brown, Larry W Swanson
doaj   +1 more source

Leukocyte Telomere Length and Cross‐Sectional and Longitudinal Variations in Gray Matter Volume and Cortical Thickness

Brain and Behavior, Volume 16, Issue 7, July 2026.
In 196 healthy older adults, shorter leukocyte telomere length predicted greater 5‐year global gray matter volume change and regional cortical thinning in the left superior parietal lobule, independent of age and sex. Abstract Background Telomere length (TL) has emerged as a candidate predictor for biological aging and age‐associated conditions, yet ...
Ezgi Yetim, Mehmet Akif Topcuoglu, Nuket Yurur Kutlay, Ajlan Tukun, Kader Karli Oguz, Ethem Murat Arsava   +5 more
wiley   +1 more source

Mapping the Disrupted Connectome in Spinocerebellar Ataxia Type 3: A Network‐Based Statistics Study Identifying Novel Therapeutic Targets for Neuromodulation

CNS Neuroscience &Therapeutics, Volume 32, Issue 7, July 2026.
This study identifies a dual pattern of structural and functional connectome disruption in SCA3 that correlates with clinical severity. Importantly, these abnormal structural connectivities are modulated by TMS, establishing them as promising imaging biomarkers and therapeutic targets for precision neuromodulation intervention.
Lan Ou, Chaoyang Zhou, Xingang Wang, Linfeng Shi, Peiling Ou, Chaodong Xiang, Hui Chen, Xi Chen, Bijia Wang, Wei Chen, Jian Wang, Zhiliang Long, Chen Liu   +12 more
wiley   +1 more source

Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice

Nature Communications
The sympathetic nervous system is crucial for responding to environmental changes. This regulation is coordinated by the spinal sympathetic preganglionic neurons (SPNs), innervating both postganglionic neurons and the adrenal gland.
Yukiko Harima, Masafumi Tsurutani, Serika Yamada, Shuntaro Uchida, Kengo Inada, Mitsue Hagihara, Satsuki Irie, Mayo Shigeta, Takaya Abe, Yukiko U. Inoue, Takayoshi Inoue, Kazunari Miyamichi   +11 more
doaj   +1 more source

Multiscale Exploration of Mouse Brain Microstructures Using the Knife-Edge Scanning Microscope Brain Atlas

Frontiers in Neuroinformatics, 2011
Connectomics is the study of the full connection matrix of the brain.Recent advances in high-throughput, high-resolution 3D microscopy methodshave enabled the imaging of whole small animal brains at a sub-micrometerresolution, potentially opening the ...
Ji Ryang Chung, Chul eSung, David eMayerich, Jaerock eKwon, Daniel E Miller, Todd eHuffman, Louise C Abbott, John eKeyser, Yoonsuck eChoe   +8 more
doaj   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source