Results 1 to 10 of about 233,602 (313)

Developmental Changes of Human Neural Progenitor Cells Grafted into the Ventricular System and Prefrontal Cortex of Mouse Brain in Utero

Cells, 2023
The transplantation of neural progenitors into a host brain represents a useful tool to evaluate the involvement of cell-autonomous processes and host local cues in the regulation of neuronal differentiation during the development of the mammalian brain.
Maria Llach Pou, Camille Thiberge, Michiel Van der Zwan, Annousha Devi Govindan, Stéphanie Pons, Uwe Maskos, Isabelle Cloëz-Tayarani   +6 more
doaj   +1 more source

Functional maturation of human iPSC-derived pyramidal neurons in vivo is dependent on proximity with the host tissue

Frontiers in Cellular Neuroscience, 2023
Human induced pluripotent stem cells (hiPSCs) have been used extensively in vitro to model early events in neurodevelopment. Because of a number of shortcomings, previous work has established a potential to use these cells in vivo after transplantation ...
Célia Raïs, Célia Raïs, Daniela Gaspar Santos, Daniela Gaspar Santos, Giulia Sansone, Stéphane Blanchard, Jean-Pierre Bourgeois, Bernd Jagla, Baptiste Saudemont, Laurène Schlick, Stéphanie Pons, Uwe Maskos   +11 more
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Recent Progress of Optoelectronic and All‐Optical Neuromorphic Devices: A Comprehensive Review of Device Structures, Materials, and Applications

Advanced Intelligent Systems, 2021
Conventional von Neumann–based computing systems have inherent limitations such as high hardware complexity, relatively inferior energy efficiency, and low bandwidth.
Seungho Song, Jeehoon Kim, Sung Min Kwon, Jeong‐Wan Jo, Sung Kyu Park, Yong‐Hoon Kim   +5 more
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Subcellular sorting of neuregulins controls the assembly of excitatory-inhibitory cortical circuits

eLife, 2020
The assembly of specific neuronal circuits relies on the expression of complementary molecular programs in presynaptic and postsynaptic neurons. In the cerebral cortex, the tyrosine kinase receptor ErbB4 is critical for the wiring of specific populations
David Exposito-Alonso, Catarina Osório, Clémence Bernard, Sandra Pascual-García, Isabel del Pino, Oscar Marín, Beatriz Rico   +6 more
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Clusters of synaptic inputs on dendrites of layer 5 pyramidal cells in mouse visual cortex

eLife, 2016
The spatial organization of synaptic inputs on the dendritic tree of cortical neurons plays a major role for dendritic integration and neural computations, yet, remarkably little is known about it.
Onur Gökçe, Tobias Bonhoeffer, Volker Scheuss   +2 more
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Optimal Self-Induced Stochastic Resonance in Multiplex Neural Networks: Electrical vs. Chemical Synapses

Frontiers in Computational Neuroscience, 2020
Electrical and chemical synapses shape the dynamics of neural networks, and their functional roles in information processing have been a longstanding question in neurobiology.
Marius E. Yamakou, Marius E. Yamakou, Poul G. Hjorth, Erik A. Martens, Erik A. Martens, Erik A. Martens   +5 more
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Research Progress on the Application of Topological Phase Transition Materials in the Field of Memristor and Neuromorphic Computing

Sensors, 2023
Topological phase transition materials have strong coupling between their charge, spin orbitals, and lattice structure, which makes them have good electrical and magnetic properties, leading to promising applications in the fields of memristive devices ...
Runqing Zhang, Rui Su, Chenglin Shen, Ruizi Xiao, Weiming Cheng, Xiangshui Miao   +5 more
doaj   +1 more source

Connexin36 Expression in the Mammalian Retina: A Multiple-Species Comparison

Frontiers in Cellular Neuroscience, 2017
Much knowledge about interconnection of human retinal neurons is inferred from results on animal models. Likewise, there is a lack of information on human retinal electrical synapses/gap junctions (GJ).
Tamás Kovács-Öller, Tamás Kovács-Öller, Tamás Kovács-Öller, Gábor Debertin, Gábor Debertin, Gábor Debertin, Márton Balogh, Márton Balogh, Márton Balogh, Alma Ganczer, Alma Ganczer, Alma Ganczer, József Orbán, József Orbán, József Orbán, Miklós Nyitrai, Miklós Nyitrai, Miklós Nyitrai, Lajos Balogh, Orsolya Kántor, Orsolya Kántor, Orsolya Kántor, Béla Völgyi, Béla Völgyi, Béla Völgyi, Béla Völgyi   +25 more
doaj   +1 more source

Neuromorphic functionality of ferroelectric domain walls

Neuromorphic Computing and Engineering, 2023
Mimicking and replicating the function of biological synapses with engineered materials is a challenge for the 21st century. The field of neuromorphic computing has recently seen significant developments, and new concepts are being explored. One of these
Pankaj Sharma, Jan Seidel
doaj   +1 more source

Quantitative Proteomics of Synaptosomal Fractions in a Rat Overexpressing Human DISC1 Gene Indicates Profound Synaptic Dysregulation in the Dorsal Striatum

Frontiers in Molecular Neuroscience, 2018
Disrupted-in-schizophrenia 1 (DISC1) is a key protein involved in behavioral processes and various mental disorders, including schizophrenia and major depression.
Fernando J. Sialana, An-Li Wang, Benedetta Fazari, Martina Kristofova, Roman Smidak, Svenja V. Trossbach, Carsten Korth, Joseph P. Huston, Maria A. de Souza Silva, Gert Lubec   +9 more
doaj   +1 more source