Results 41 to 50 of about 304,212 (313)
Is plasticity of synapses the mechanism of long-term memory storage?
npj Science of Learning, 2019 It has been 70 years since Donald Hebb published his formalized theory of synaptic adaptation during learning. Hebb’s seminal work foreshadowed some of the great neuroscientific discoveries of the following decades, including the discovery of long-term ...
W. Abraham, O. Jones, D. Glanzman
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A brain-wide atlas of synapses across the mouse lifespan
Science, 2020 Brain synapses through the life span Excitatory synapses connect neurons in the brain to build the circuits that enable behavior. Cizeron et al. surveyed synapses in the mouse brain from birth to old age and present the data as a community resource, the ...
Mélissa Cizeron +6 more
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Les chaînes de traction des TGV
Comptes Rendus. MécaniqueThis article describes the different components of the TGV drive trains, from the TGV SE (1st TGV) to the TGVM.
Goeres, David
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A Role for Dystonia-Associated Genes in Spinal GABAergic Interneuron Circuitry
Cell Reports, 2017 Spinal interneurons are critical modulators of motor circuit function. In the dorsal spinal cord, a set of interneurons called GABApre presynaptically inhibits proprioceptive sensory afferent terminals, thus negatively regulating sensory-motor signaling.
Juliet Zhang +9 more
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iScienceSummary: Retinal ganglion cells (RGCs) summate inputs and forward a spike train code to the brain in the form of either maintained spiking (sustained) or a quickly decaying brief spike burst (transient).
Gergely Szarka +8 more
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Translational Neuroscience, 2017 This study investigated the effects of calcium on fluorosis-induced impairment in learning and memory of offspring rats. Methods Seventy-five newly weaned female Sprague–Dawley (SD) rats were randomly divided into five groups as follows: Control group ...
Zigu Zhang +5 more
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The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb
eLife, 2017 Microglia play important roles in perinatal neuro- and synapto-genesis. To test the role of microglia in these processes during adulthood, we examined the effects of microglia depletion, via treatment of mice with the CSF-1 receptor antagonist PLX5622 ...
Ronen Reshef +6 more
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RNA, 2015 One reason we learn and remember is because synapses, the places where axons and dendrites meet, undergo experience-dependent changes whose long-lasting nature may underlie the formation and persistence of memory. Indeed, neurons use these morphological and biochemical alterations to distinguish experienced (i.e., stimulated) from naive (unstimulated ...
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Cell ReportsSummary: To better understand the function of cholinergic projection neurons in the ventral pallidum (VP), we examined behavioral responses to appetitive (APP) and aversive (AV) odors that elicited approach or avoidance, respectively.
Ronald Kim +4 more
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eLife, 2016 The mechanisms regulating synapse numbers during development and ageing are essential for normal brain function and closely linked to brain disorders including dementias. Using Drosophila, we demonstrate roles of the microtubule-associated protein Tau in
Andre Voelzmann +6 more
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