Determining the neurotransmitter concentration profile at active synapses [PDF]
, 2009 Establishing the temporal and concentration profiles of neurotransmitters during synaptic release is an essential step towards understanding the basic properties of inter-neuronal communication in the central nervous system.
Beato, M. +3 more
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Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2
Frontiers in Molecular Neuroscience, 2018 Structural and functional plasticity of synapses are critical neuronal mechanisms underlying learning and memory. While activity-dependent regulation of synaptic strength has been extensively studied, much less is known about the transcriptional control ...
Elodie De Bruyckere +11 more
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The History of the Synapse [PDF]
The Anatomical Record, 2020 ABSTRACTWhy did I choose this particular topic for my lecture rather than the history of neuroscience or the history of the neuron? Simply because I believe that every disciple has the obligation to pay homage to their mentors once in their lifetime. My formation as a neuroscientist involved three such mentors spanned across three countries.
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Endocannabinoid Release Modulates Electrical Coupling between CCK Cells Connected via Chemical and Electrical Synapses in CA1. [PDF]
, 2011 Electrical coupling between some subclasses of interneurons is thought to promote coordinated firing that generates rhythmic synchronous activity in cortical regions.
Ali eAfia +5 more
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A VLSI recurrent network of integrate-and-fire neurons connected by plastic synapses with long-term memory [PDF]
, 2003 Chicca E, Badoni D, Dante V, et al. A VLSI recurrent network of integrate-and-fire neurons connected by plastic synapses with long-term memory. IEEE Transactions on Neural Networks.
Fusi, S. +7 more
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Autophagy at the synapse [PDF]
Neuroscience Letters, 2019 As the sites of communication between neurons, synapses depend upon precisely regulated protein-protein interactions to support neurotransmitter release and reception. Moreover, neuronal synapses typically exist great distances (i.e. up to meters) away from cell bodies, which are the sources of new proteins and the major sites of protein degradation ...
Veronica Birdsall, Clarissa L. Waites
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Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses [PDF]
, 2011 Immune synapses formed by T and NK cells both show segregation of the integrin ICAM1 from other proteins such as CD2 (T cell) or KIR (NK cell).
Dustin, Michael L. +22 more
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Expression of Neurofilament Subunits at Neocortical Glutamatergic and GABAergic Synapses
Frontiers in Neuroanatomy, 2018 Neurofilaments (NFs) are neuron-specific heteropolymers that have long been considered as structural proteins. However, it has recently been documented that they may play a functional role at synapses.
Luca Bragina +3 more
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Regulation of dendritic spine morphogenesis and synapse formation by copines [PDF]
, 2006 Primary rat hippocampal culture is a well established system to study molecular mechanisms occurring during synapse formation and maturation. By closer analysis of the temporal appearance of presynaptic Bassoon and the postsynaptic proteins SynGAP, PSD ...
Galic, Milos
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HDAC6 in Diseases of Cognition and of Neurons
Cells, 2020 Central nervous system (CNS) neurodegenerative diseases are characterized by faulty intracellular transport, cognition, and aggregate regulation. Traditionally, neuroprotection exerted by histone deacetylase (HDAC) inhibitors (HDACi) has been attributed ...
Patrizia LoPresti
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