Results 21 to 30 of about 233,602 (313)

A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]

open access: yes, 2011
The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Mark J. Wall   +3 more
core   +1 more source

The Immunological Synapse [PDF]

open access: yesCancer Immunology Research, 2003
AbstractThe molecular interactions underlying regulation of the immune response take place in a nanoscale gap between T cells and antigen-presenting cells, termed the immunological synapse. If these interactions are regulated appropriately, the host is defended against a wide range of pathogens and deranged host cells.
openaire   +6 more sources

Quantification of the density of cooperative neighboring synapses required to evoke endocannabinoid signaling [PDF]

open access: yes, 2014
The spatial pattern of synapse activation may impact on synaptic plasticity. This applies to the synaptically-evoked endocannabinoid-mediated short-term depression at the parallel fiber (PF) to Purkinje cell synapse, the occurrence of which requires ...
Pachoud, B   +9 more
core   +1 more source

Structure-function analysis on the level of individual synapses [PDF]

open access: yes, 2010
Excitatory synapses in the mammalian brain are made on small protrusions of the postsynaptic cell called dendritic spines. Dendritic spines are highly variable in their morphology and in their microanatomy (e.g. presence of subsynaptic organelles). It is
Holbro, Niklaus
core   +1 more source

Monoacylated Cellular Prion Proteins Reduce Amyloid-β-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage

open access: yesBiology, 2015
Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) and the loss of synapses. Aggregation of the cellular prion protein (PrPC) by Aβ oligomers induced synapse damage in cultured neurons.
Ewan West   +3 more
doaj   +1 more source

Neuron Class and Target Variability in the Three-Dimensional Localization of SK2 Channels in Hippocampal Neurons as Detected by Immunogold FIB-SEM

open access: yesFrontiers in Neuroanatomy, 2021
Small-conductance calcium-activated potassium (SK) channels are crucial for learning and memory. However, many aspects of their spatial organization in neurons are still unknown.
Rafael Luján   +8 more
doaj   +1 more source

A VLSI array of low-power spiking neurons and bistable synapses with spike-timing dependent plasticity [PDF]

open access: yes, 2006
Indiveri G, Chicca E, Douglas RJ. A VLSI array of low-power spiking neurons and bistable synapses with spike-timing dependent plasticity. IEEE Transactions on Neural Networks.
Rodney Douglas   +8 more
core   +1 more source

Posthatching development of synapses in the neuropil of nucleus rotundus of the zebra finch: a quantitative electron microscopic study [PDF]

open access: yes, 1986
Nixdorf B, Bischof H-J. Posthatching development of synapses in the neuropil of nucleus rotundus of the zebra finch: a quantitative electron microscopic study. The Journal of Comparative Neurology.
Nixdorf, Barbara   +3 more
core   +1 more source

Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

open access: yeseLife, 2017
Beyond its role in parturition and lactation, oxytocin influences higher brain processes that control social behavior of mammals, and perturbed oxytocin signaling has been linked to the pathogenesis of several psychiatric disorders.
Silvia Ripamonti   +14 more
doaj   +1 more source

Exercise Intervention Promotes the Growth of Synapses and Regulates Neuroplasticity in Rats With Ischemic Stroke Through Exosomes

open access: yesFrontiers in Neurology, 2021
Background: Stroke is the leading cause of death and disability. Exercise produces neuroprotection by improving neuroplasticity. Exercise can induce exosome production.
Chen Li   +3 more
doaj   +1 more source

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