Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro +8 more
wiley +1 more source
Study of Innovative Connector for Steel–Concrete Composite Structures
The paper presents an analysis of the innovative connector for manufacturing a steel–concrete composite beam. The connector consists of a corrugated metal sheet in the shape of a dovetail and shot nails. The nails are shot through the sheet fold into the
Anna Derlatka +3 more
doaj +1 more source
Electrical cable connector-clamp has smooth exterior surface [PDF]
Electrical cable connector-clamp fitted with a collet has a smooth exterior surface that can be easily gripped.
core +1 more source
A murine cellular model of necroinflammation displays RAGE‐dependent cytokine induction that connects to hepatoma cell injury [PDF]
Malte Bachmann +4 more
openalex +1 more source
Connecting the Dots: Public Health, Clinical, and Community Connections to Improve Contraception Access [PDF]
Ellen Pliska +2 more
openalex +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner +6 more
wiley +1 more source
Diffusion bonding makes strong seal at flanged connector [PDF]
Copper strip seals a high pressure fluid system connector so that it is insensitive to relaxation of the bolt loads. The copper strip is diffusion bonded to the surfaces of the connector flange by application of high pressure and ...
Gitzendanner, L. G. +2 more
core +1 more source
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp +13 more
wiley +1 more source
Spacecraft Electrical Connector Selection and Application Processes [PDF]
This assessment was initiated by the NASA Engineering & Safety Center (NESC) after a number of recent "high profile" connector problems, the most visible and publicized of these being the problem with the Space Shuttle's Engine Cut-Off System cryogenic ...
Davis, Mitchell I +3 more
core +1 more source

