Results 61 to 70 of about 300,894 (355)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Single connector provides safety fuses for multiple lines [PDF]

open access: yes, 1966
Fuse-bearing sleeve which is inserted between the male and female members of a multiple-line connector contains a safety fuse for each pin of the connector assembly.
Weber, G. J.
core   +1 more source

On Packing Connectors

open access: yesJournal of Combinatorial Theory, Series B, 1998
Let \(G=(V,E)\) be an undirected graph and \(\{S,T\}\) a partition of \(V\). Then a set of edges \(F\subseteq E\) such that every component of the subgraph \((V,F)\) intersects both \(S\) and \(T\), is called an \(S\)--\(T\) connector. In general a subpartition \(W\) of a set \(X\) is a collection of pairwise disjoint nonempty subsets of \(X\); and if--
Keijsper, J.C.M., Schrijver, A.
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Digital twin based stress field prediction method for offshore floating power generation platform connectors

open access: yesZhongguo Jianchuan Yanjiu
ObjectivesWhen assessing the safety of the connectors of a multi-module offshore floating power generation platform, in order to compensate for the inability to carry out the real-time monitoring of the structural stress field across the whole domain due
Yu CAO, Lin GAN, Tao ZHANG
doaj   +1 more source

On so-called adversative nisi

open access: yesPallas, 2016
This paper is concerned with certain semantic and pragmatic properties of the Latin connector nisi. The discussion is structured in three sections. The first gives a short introduction of the main functions of nisi identified in the scholarship on the ...
Giovanbattista Galdi
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Aspects of coordination by junction in Old Romanian [PDF]

open access: yesDiacronia, 2016
The approach of coordination by junction in a diachronic perspective aimed at establishing the discursive values of the connectors, in the integrated frame of these syntactic relation patterns, and the manner in which the literary norm selected the ...
Ștefan Găitănaru
doaj   +1 more source

Partial Connector Colouring [PDF]

open access: yes, 2012
Connector colouring provided an intuitive semantics of Reo connectors which lead to effective implementation techniques, first based on computing colouring tables directly, and later on encodings of colouring into constraints. One weakness of the framework is that it operates globally, giving a colouring to all primitives of the connector in lock-step,
Clarke D., Proenca J.
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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