Results 71 to 80 of about 1,652,273 (313)

Three-Dimensional Finite-Element Analysis of the Short-Time and Peak Withstand Current Tests in Substation Connectors

Energies, 2016
Power devices intended for high-voltage systems must be tested according to international standards, which includes the short-time withstand current test and peak withstand current test.
Francesca Capelli, Jordi-Roger Riba, Joan Pérez   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

RADAR-base/radar-helm-charts: radar-jdbc-connector-0.5.1

, 2023
<p>A Helm chart for RADAR-base JDBC Kafka connector. This is a fork of the Kafka JDBC connector which allows data from topics to be imported into JDBC databases (including TimescaleDB databases which is used in the dashboard pipeline).</p ...
Joris Borgdorff, Pauline Conde, Heet Sankesara, Yatharth Ranjan, Keyvan   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Partial Connector Colouring [PDF]

, 2012
Connector colouring provided an intuitive semantics of Reo connectors which lead to effective implementation techniques, first based on computing colouring tables directly, and later on encodings of colouring into constraints. One weakness of the framework is that it operates globally, giving a colouring to all primitives of the connector in lock-step,
Dave Clarke 0001, José Proença
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

On so-called adversative nisi

Pallas, 2016
This paper is concerned with certain semantic and pragmatic properties of the Latin connector nisi. The discussion is structured in three sections. The first gives a short introduction of the main functions of nisi identified in the scholarship on the ...
Giovanbattista Galdi
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Analytical and Experimental Investigation of a Three-Module VLFS Connector Based on an Elastic Beam Model

Journal of Marine Science and Engineering
Very large floating structures (VLFSs) typically employ a modular design approach to mitigate significant hydroelastic loads. A mooring system is commonly employed to maintain the position and heading of a VLFS against the forces of waves, wind, and ...
Yongheng Wang, Xuefeng Wang, Shengwen Xu, Lei Wang   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source