Results 181 to 190 of about 55,399 (296)

Novel 1-bit hybrid reconfigurable intelligent surface. [PDF]

Sci Rep
Keshmiri S, Jayasuriya S, Imani MF.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Towards a minimum viable dataspace for the CEDS public sector: An initial implementation. [PDF]

Data Brief
Nikolakopoulos A, Dede G, Ipektsidis C, Kefalakis N, Zervoudakis P, Papanatsios F.   +5 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Design and Technical Validation of a Novel O2 Mixed Fitting for Dual Connection in Medical Oxygen Delivery Systems. [PDF]

Med Devices (Auckl)
Quintero Osorio OI, Basançelebi B, Dos Santos EDC, Prada SI, Lemos DA, Domínguez AF, Esquinas AM.   +6 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Research on the anti-pull performance of a novel small-diameter steel tube-stud grouting connector. [PDF]

PLoS One
Zhou MS, Bao EH, Luo CJ, Wang JF, Wu YS, Xiao CJ.   +5 more
europepmc   +1 more source

Direct electrical measurement of tube-voltage waveforms in mammography systems using ALDEN-type high-voltage connectors. [PDF]

Med Phys
Negishi T, Shinsho K, Abe S, Ogura I.
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Case Report: Surgical management of thoracic chondrodysplasia in children: complete mobile thoracic replacement. [PDF]

Front Surg
Louis L, Harper L, Maes JD, Lavrand F.
europepmc   +1 more source