Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Needle-free connectors in tunneled central venous catheters for hemodialysis: A prospective single-centre safety and feasibility study. [PDF]
Leskovar B, Furlan T.
europepmc +1 more source
Fiber optics for aircraft engine/inlet control [PDF]
NASA programs that focus on the use of fiber optics for aircraft engine/inlet control are reviewed. Fiber optics for aircraft control is attractive because of its inherent immunity to EMI and RFI noise.
Baumbick, R. J.
core +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Biomechanical properties of double-headed pedicle screws and parallel connectors in thoracolumbar extension revision fixation: a finite element analysis. [PDF]
Wang H +8 more
europepmc +1 more source
A Mobile Auxin Signal Connects Temperature Sensing in Cotyledons with Growth Responses in Hypocotyls
Julia Bellstäedt +7 more
openalex +1 more source
Research and Development of Strain Clamp and Connecting Tube of 1520mm2 Large-section Conductor [PDF]
Kuanjun Zhu +6 more
openalex +1 more source
Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein +13 more
wiley +1 more source
The key technologies of a computer-aided design system for removable partial denture frameworks. [PDF]
Ma G +5 more
europepmc +1 more source

