Results 121 to 130 of about 25,696 (242)
GAP JUNCTION: Emphasis on Connexin 43
Acta Scientiae et TechnicaeThe junctions of the cell are complex structures that play a fundamental role in cellular communication. They are morphologically distinct and are divided into occlusion junctions, adherens junctions and gap junctions. This review has the objective of providing the main information about the gap junctions demonstrating its components and highlighting ...
Gabriella Oliveira Alves Moreira de Carvalho +2 more
openaire +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source
Transduction of Cell Survival Signals by Connexin-43 Hemichannels [PDF]
, 2002 Lilian I. Plotkin +2 more
openalex +1 more source
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
Advanced Science, Volume 13, Issue 3, 14 January 2026.This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen +13 more
wiley +1 more source
Identification of Two Regulatory Elements within the Promoter Region of the Mouse Connexin 43 Gene [PDF]
, 1995 Zhiqing Chen +5 more
openalex +1 more source
Mitochondrial Adaptation to Mechanical Stress in Cardiac Ageing and Disease
Advanced Science, Volume 13, Issue 4, 19 January 2026.Mechanical forces shape the heart's energy factories. This review explores how mitochondria in cardiac cells sense and respond to biomechanical stress, altering their structure, positioning, and metabolism. By linking mechanical cues to mitochondrial adaptation, the article highlights pathways driving heart disease and points to new strategies for ...
Aishwarya Prakash, Thomas Iskratsch
wiley +1 more source
Protein Kinase C Regulates Meiosis in Mammalian Oocytes
BioEssays, Volume 48, Issue 1, January 2026.Protein kinase C (PKC) participates in the regulation of mammalian oocyte meiosis. PKC is involved in meiosis resumption in prophase I and in the stabilization of meiosis I and meiosis II spindles. PKC stimulates the maturation‐promoting factor during fertilization and stabilizes the mitotic spindle during early embryo development. ABSTRACT The protein
Jaroslav Kalous +2 more
wiley +1 more source