Results 141 to 150 of about 195,400 (281)
Expression and localization of connexin 43 in glioblastoma
The bystander effect is essential to the success of the Herpes simplex virus thymidine kinase (TK)/gancyclovir (GCV) strategy for cancer therapy. It consists of the transfer of phosphorylated GCV from TK+ cells to neighbouring TK− cells via gap junctions made up of connexin molecules.
Peter V Gould+3 more
openaire +2 more sources
Two novel GJA1 variants in oculodentodigital dysplasia
Background Oculodentodigital dysplasia (ODDD) is a rare disorder with pleiotropic effects involving multiple body systems, caused by mutations in the gap junction protein alpha 1 (GJA1) gene. GJA1 gene encodes a polytopic connexin membrane protein, Cx43,
Nikolai P. Pace+6 more
doaj +1 more source
Hilbertian Toposes Epsilon Toposes [PDF]
We study Hilbert's epsilon calculus and Hilbert's partial epsilon calculus in toposes.
arxiv
<p>Rationale: Dedifferentiation of vascular smooth muscle cells (VSMC) leading to a proliferative cell phenotype significantly contributes to the development of atherosclerosis.
Best, A.K.+12 more
core +1 more source
Endothelial TRPV4–Cx43 signalling complex regulates vasomotor tone in resistance arteries
Abstract figure legend In this study, we investigate, for the first time, the role of endothelial Cx43 hemichannels (hCx43) in the regulation of vasomotor tone. We discovered that TRPV4 channels and Cx43 are in proximity within the endothelium of mouse arterioles.
Pía C. Burboa+7 more
wiley +1 more source
Cadmium (Cd) is a significant environmental contaminant known for its potential hepatotoxic effects. However, the precise mechanisms underlying Cd-induced hepatotoxicity have yet to be fully understood.
Yuntian Duan+10 more
doaj
Chronology of Events Accompanying Follicular Atresia in Hypophysectomized Ewes. Changes in Levels of Steroidogenic Enzymes, Connexin 43, Insulin-Like Growth Factor II/Mannose 6 Phosphate Receptor, Extracellular Matrix Components, and Matrix Metalloproteinases1 [PDF]
Clotilde Huet+5 more
openalex +1 more source
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich+9 more
wiley +1 more source
Tyrosine Phosphorylation of Connexin 43 by v-Src Is Mediated by SH2 and SH3 Domain Interactions [PDF]
Martha Y. Kanemitsu+4 more
openalex +1 more source