From Adipose Tissue to Cardiac Repair: Extracellular Vesicles in Cardiovascular Regeneration
ABSTRACT Adipose‐derived extracellular vesicles (ADEVs) secreted by adipose tissue have gained increasing attention due to their regenerative and immunomodulatory properties in cardiovascular diseases. They carry proteins, lipids, and nucleic acids that mediate intercellular communication and influence cardiac pathophysiology. In atherosclerosis, ADEVs
Karolina Ignaczak +6 more
wiley +1 more source
Connexin 43 and cellular senescence
Carpintero-Fernandez, P. +7 more
openaire +1 more source
Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G. +5 more
wiley +1 more source
SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley +1 more source
Abstract figure legend Cells and conductances contributing to spontaneous activity in the lower urinary tract. Bladder and urethra exhibit spontaneous contractions at both cellular and tissue levels. Both detrusor and urethral smooth muscle cells display activity that is regular and rhythmic.
Bernard T. Drumm +3 more
wiley +1 more source
Connexin26 and 43 play a role in regulating pro-inflammatory events in the epidermis [PDF]
Bartholomew, Christopher +4 more
core +1 more source
Connexin-43 Restoration Alleviates Desmosomal Arrhythmogenic Cardiomyopathy. [PDF]
Zhang J +18 more
europepmc +1 more source
Molecular Modeling and Dynamics of a Complete Connexin-43 Gap Junction Channel in Various Phosphorylation States. [PDF]
Gao Y, Zuo J, Falk MM, Im W.
europepmc +1 more source
Prenatal lipopolysaccharide exposure programs cardiac fibrosis via dysregulating of connexin 43 in offspring rats. [PDF]
Wen Y, Yuan Y, Zhang H, Liu Y.
europepmc +1 more source
Injury-induced connexin 43 expression regulates endothelial wound healing. [PDF]
Sedovy MW +10 more
europepmc +1 more source

