Results 1 to 10 of about 98,351 (351)

Understanding the Molecular and Cell Biological Mechanisms of Electrical Synapse Formation

Frontiers in Neuroanatomy, 2020
In this review article, we will describe the recent advances made towards understanding the molecular and cell biological mechanisms of electrical synapse formation. New evidence indicates that electrical synapses, which are gap junctions between neurons,
E. Anne Martin, Abagael M. Lasseigne, Adam C. Miller   +2 more
doaj   +1 more source

Gap Junctions Contribute to the Regulation of Walking-Like Activity in the Adult Mudpuppy (Necturus Maculatus). [PDF]

PLoS ONE, 2016
Although gap junctions are widely expressed in the developing central nervous system, the role of electrical coupling of neurons and glial cells via gap junctions in the spinal cord in adults is largely unknown.
Igor Lavrov, Lyle Fox, Jun Shen, Yingchun Han, Jianguo Cheng   +4 more
doaj   +1 more source

Gap Junctions Regulate Seizure Activity – But in Unexpected Ways

, 2013
Seizures are a poorly understood neurophysiological state epitomized by hypersynchronous excitatory brain activity. This chapter will explore the experimental and theoretical basis for the involvement of gap junctions in the generation of seizure ...
Voss, LJ, Sleigh, James, James W. Sleigh, Logan J. Voss   +3 more
core   +1 more source

AGE-BSA down-regulates endothelial connexin43 gap junctions

BMC Cell Biology, 2011
Background Advanced glycation end products generated in the circulation of diabetic patients were reported to affect the function of vascular wall. We examined the effects of advanced glycation end products-bovine serum albumin (AGE-BSA) on endothelial ...
Wang Hsueh-Hsiao, Lin Yi-Chun, Chen Heng-Ju, Liu Hung-Jen, Wang Chi-Young, Hung Ta-Chuan, Yeh Hung-I   +6 more
doaj   +1 more source

Modelling the effect of gap junctions on tissue-level cardiac electrophysiology [PDF]

Electronic Proceedings in Theoretical Computer Science, 2012
When modelling tissue-level cardiac electrophysiology, continuum approximations to the discrete cell-level equations are used to maintain computational tractability.
Doug Bruce, Pras Pathmanathan, Jonathan P. Whiteley   +2 more
doaj   +1 more source

Formation mechanism and resistance fluctuations of atomic sized junctions [PDF]

, 2009
In this thesis we focus on: (a) Feedback controlled electromigration in four-terminal nano-junctions, where a new technique to control electromigration in Au nano-junction is presented.
Wu Hawellek, ZhengMing
core   +1 more source

Sub-micron thin film intrinsic Josephson junctions

, 2003
We have fabricated sub-micron intrinsic Josephson junctions in thin films of Tl-Ba-Ca-Cu-O using two differing techniques suited to different applications. By using lateral focussed ion-beam milling we have created arrays of intrinsic junctions in c-axis
Grovenor, CRM, Schneidewind, H, Kuzhakhmetov, AR, Bell, C, Warburton, PA, Grovenor, Christopher, Wu, H, Burnell, G, Bell, Chris, Blamire, MG   +9 more
core   +1 more source

Role of gap junctions in the propagation of the cardiac action potential [PDF]

, 2004
Gap junctions play a pivotal role for the velocity and the safety of impulse propagation in cardiac tissue. Under physiologic conditions, the specific subcellular distribution of gap junctions together with the tight packaging of the rod-shaped ...
Rohr, Stephan
core   +1 more source

Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors

, 2010
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Melin, Sofia M., Jacobson, Gregory M., Voss, Logan J., D. Alistair Steyn-Ross, Cursons, Raymond T., Steyn-Ross, D. Alistair, Sleigh, James W., James W. Sleigh, Logan J. Voss, Steyn-Ross, Moira L., Moira L. Steyn-Ross, Gregory M. Jacobson, Sofia M. Melin, Jonathan P. Mason, Mason, Jonathan P., Ray T. Cursons   +15 more
core   +1 more source

The role of endothelial junctions in the regulation of the extravasation of tumor cells. A historical reappraisal

Frontiers in Oncology
Endothelial cells lining the vessel wall are connected by adherent, tight and gap junctions. Adherent junctions are common to all endothelial cells, whereas tight and gap junctions graduate within different vascular segments.
Domenico Ribatti
doaj   +1 more source