Understanding the Molecular and Cell Biological Mechanisms of Electrical Synapse Formation [PDF]
Frontiers in Neuroanatomy, 2020 In this review article, we will describe the recent advances made towards understanding the molecular and cell biological mechanisms of electrical synapse formation. New evidence indicates that electrical synapses, which are gap junctions between neurons,
E. Anne Martin +2 more
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Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold. [PDF]
PLoS Genetics, 2023 Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies electrical transmission.
Jennifer Carlisle Michel +21 more
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Long-term potentiation in an innexin-based electrical synapse [PDF]
Scientific Reports, 2018 Electrical synapses are formed by two unrelated gap junction protein families, the primordial innexins (invertebrates) or the connexins (vertebrates). Although molecularly different, innexin- and connexin-based electrical synapses are strikingly similar ...
Georg Welzel, Stefan Schuster
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The ever-changing electrical synapse. [PDF]
Curr Opin Neurobiol, 2014 A wealth of research has revealed that electrical synapses in the central nervous system exhibit a high degree of plasticity. Several recent studies, particularly in the retina and inferior olive, highlight this plasticity. Three classes of mechanisms can alter electrical coupling over time courses ranging from milliseconds to days. Changes of membrane
O'Brien J.
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The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact [PDF]
eLifeMost nervous systems combine both transmitter-mediated and direct cell–cell communication, known as ‘chemical’ and ‘electrical’ synapses, respectively. Chemical synapses can be identified by their multiple structural components.
Sandra P Cárdenas-García +2 more
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A new measure for the strength of electrical synapses [PDF]
Frontiers in Cellular Neuroscience, 2015 Electrical synapses, like chemical synapses, mediate intraneuronal communication. Electrical synapses are typically quantified by subthreshold measurements of coupling, which fall short in describing their impact on spiking activity in coupled neighbors.
Julie S Haas
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Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling [PDF]
eLifeElectrical synapses containing Connexin 36 (Cx36) represent the main means for direct electrical communication among neurons in the mammalian nervous system. However, little is known about the protein complexes that constitute these synapses.
Stephan Tetenborg +13 more
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Neurobeachin controls the asymmetric subcellular distribution of electrical synapse proteins [PDF]
Current Biology, 2023 Adam Miller +2 more
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Calmodulin Binding to Connexin 35: Specializations to Function as an Electrical Synapse [PDF]
International Journal of Molecular Sciences, 2020 Jaya Aseervatham +2 more
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The electrical synapse: Molecular complexities at the gap and beyond [PDF]
Developmental Neurobiology, 2017 Adam Miller, Alberto Pereda
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