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Understanding the Molecular and Cell Biological Mechanisms of Electrical Synapse Formation [PDF]

open access: yesFrontiers in Neuroanatomy, 2020
In this review article, we will describe the recent advances made towards understanding the molecular and cell biological mechanisms of electrical synapse formation. New evidence indicates that electrical synapses, which are gap junctions between neurons,
E. Anne Martin   +2 more
doaj   +4 more sources

Electrical synapse structure requires distinct isoforms of a postsynaptic scaffold. [PDF]

open access: yesPLoS Genetics, 2023
Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies electrical transmission.
Jennifer Carlisle Michel   +21 more
doaj   +2 more sources

Long-term potentiation in an innexin-based electrical synapse [PDF]

open access: yesScientific Reports, 2018
Electrical synapses are formed by two unrelated gap junction protein families, the primordial innexins (invertebrates) or the connexins (vertebrates). Although molecularly different, innexin- and connexin-based electrical synapses are strikingly similar ...
Georg Welzel, Stefan Schuster
doaj   +2 more sources

The components of an electrical synapse as revealed by expansion microscopy of a single synaptic contact [PDF]

open access: yeseLife
Most nervous systems combine both transmitter-mediated and direct cell–cell communication, known as ‘chemical’ and ‘electrical’ synapses, respectively. Chemical synapses can be identified by their multiple structural components.
Sandra P Cárdenas-García   +2 more
doaj   +2 more sources

Calmodulin Binding to Connexin 35: Specializations to Function as an Electrical Synapse [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Jaya Aseervatham   +2 more
exaly   +2 more sources

Isolation of Immunocomplexes from Zebrafish Brain

open access: yesBio-Protocol, 2023
Zebrafish is an excellent model to study vertebrate neurobiology, but its synaptic components that mediate and regulate fast electrical synaptic transmission are largely unidentified.
Jennifer Michel, Adam Miller
doaj   +1 more source

Artificial optoelectronic synaptic characteristics of Bi2FeMnO6 ferroelectric memristor for neuromorphic computing

open access: yesMaterials & Design, 2022
Photoelectric synapse is a new type of artificial synapse that combines light pulse excitation and electrical pulse excitation, and is an important component for the development of neuromorphic hardware.
Wen-Min Zhong   +3 more
doaj   +1 more source

Electrical synaptic transmission requires a postsynaptic scaffolding protein

open access: yeseLife, 2021
Electrical synaptic transmission relies on neuronal gap junctions containing channels constructed by Connexins. While at chemical synapses neurotransmitter-gated ion channels are critically supported by scaffolding proteins, it is unknown if channels at ...
Abagael M Lasseigne   +9 more
doaj   +1 more source

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