Gap Junctions in Ischemia-Related Ventricular Arrhythmia [PDF]
Majalah Kardiologi Indonesia, 2013 Cardiovascular diseases are the leading cause of death worldwide, with isch-emic heart disease being the most common entity. Ventricular arrhythmia is one of the complications of ischemia that can result in sudden cardiac death.
Berlian Idriansyah Idris, Yoga Yuniadi
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Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. [PDF]
PLoS Genetics, 2016 Gap junctions are present in both vertebrates and invertebrates from nematodes to mammals. Although the importance of gap junctions has been documented in many biological processes, the molecular mechanisms underlying gap junction dynamics remain unclear.
Lingfeng Meng, Chia-hui Chen, Dong Yan
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Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts [PDF]
, 2008 The inaccessibility of osteocytes due to their embedment in the calcified bone matrix in vivo has precluded direct demonstration that osteocytes use gap junctions as a means of intercellular communication.
Sugawara, Yasuyo +6 more
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Gap junctions, dendrites and resonances : a recipe for tuning network dynamics [PDF]
, 2013 Gap junctions, also referred to as electrical synapses, are expressed along the entire central nervous system and are important in mediating various brain rhythms in both normal and pathological states.
Michieletto, Davide +5 more
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Connexins in neurons and glia: targets for intervention in disease and injury
Neural Regeneration Research, 2015 Both neurons and glia throughout the central nervous system are organized into networks by gap junctions. Among glia, gap junctions facilitate metabolic homeostasis and intercellular communication.
Keith B Moore, John O′Brien
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Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments
The Journal of Clinical Investigation, 2023 Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap junctions are responsible for the propagation of electrical and chemical signals between myocardial cells and cells of the specialized conduction system in order to ...
Luc Leybaert +8 more
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Nitric oxide enhances de novo formation of endothelial gap junctions [PDF]
, 2003 Objective: Gap junctions (formed by connexins, Cx) are important for functional coordination of cells in the vascular wall. However, little is known about their physiological regulation in this tissue.
Gloe, Torsten +3 more
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Abundance of gap junctions at glutamatergic mixed synapses in adult Mosquitofish spinal cord neurons
Frontiers in Neural Circuits, 2014 Dye-coupling, whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the ...
Jose L Serrano-Velez +8 more
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Studying gap junctions with PARIS
eLife, 2019 A new genetically encoded system manipulates the pH inside cells to detect whether they are coupled to each other.
Daniel R Kick, David J Schulz
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Frontiers in Cellular Neuroscience, 2021 Electrical synaptic transmission is an essential form of interneuronal communication which is mediated by gap junctions that permit ion flow. Three gene families (connexins, innexins, and pannexins) have evolved to form gap junctional channels.
Qiqian Wang, Shenquan Liu
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