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Gap junctions [PDF]

open access: yesCurrent Biology, 2013
In vertebrates and invertebrates, signaling among neurons is most commonly mediated by chemical synapses. At these synapses neurotransmitter released by presynaptic neurons is detected by receptors on the postsynaptic neurons, leading to an influx of ions through the receptors themselves or through channels activated by intracellular signaling ...
Shimizu, Kazumichi, Stopfer, Mark
core   +4 more sources

Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size [PDF]

open access: yesFrontiers in Ophthalmology, 2023
Gap junctions transmit electrical signals in neurons and serve metabolic coupling and chemical communication. Gap junctions are made of intercellular channels with large pores, allowing ions and small molecules to permeate.
Chunxu Yuan   +6 more
doaj   +2 more sources

Adherens, tight, and gap junctions in ependymal cells: A systematic review of their contribution to CSF-brain barrier [PDF]

open access: yesFrontiers in Neurology, 2023
IntroductionThe movement of fluids and solutes across the ependymal barrier, and their changes in physiologic and disease states are poorly understood.
Riccardo Serra   +3 more
doaj   +2 more sources

Gap Junctions in C. elegans [PDF]

open access: yesFrontiers in Physiology, 2014
As in other multicellular organisms, the nematode Caenorhabditis elegans uses gap junctions to provide direct cell-to-cell contact. The nematode gap junctions are formed by innexins (invertebrate analogs of the connexins); a family of proteins that ...
Karina eSimonsen   +3 more
doaj   +3 more sources

Astrocyte gap junctions and Kir channels contribute to K+ buffering and regulate neuronal excitability [PDF]

open access: yesFrontiers in Cellular Neuroscience
Astrocytes are connected in a functional syncytium via gap junctions, which contribute to the maintenance of extracellular K+ homeostasis. The prevailing hypothesis is that K+ released during neuronal firing is taken up by astrocytes via Kir channels and
Danica Bojovic   +6 more
doaj   +2 more sources

Gap junctions and epileptic seizures--two sides of the same coin? [PDF]

open access: yesPLoS ONE, 2011
Electrical synapses (gap junctions) play a pivotal role in the synchronization of neuronal ensembles which also makes them likely agonists of pathological brain activity.
Vladislav Volman   +2 more
doaj   +3 more sources

Gap Junctions in Ischemia-Related Ventricular Arrhythmia

open access: yesMajalah Kardiologi Indonesia, 2013
Cardiovascular diseases are the leading cause of death worldwide, with isch-emic heart disease being the most common entity. Ventricular arrhythmia is one of the complications of ischemia that can result in sudden cardiac death.
Berlian Idriansyah Idris, Yoga Yuniadi
doaj   +3 more sources

Gap junctions.

open access: yesDenshi kenbikyo, 1988
Proceedings of the international conference on gap junctions held at Pacific Grove, California, July 6-10 ...
Hertzberg, Elliot L.,   +2 more
openaire   +2 more sources

Contribution of large-pore channels to inflammation induced by microorganisms

open access: yesFrontiers in Cell and Developmental Biology, 2023
Plasma membrane ionic channels selectively permeate potassium, sodium, calcium, and chloride ions. However, large-pore channels are permeable to ions and small molecules such as ATP and glutamate, among others.
José L. Vega   +6 more
doaj   +1 more source

Gap Junctions [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2009
Gap junctions are aggregates of intercellular channels that permit direct cell-cell transfer of ions and small molecules. Initially described as low-resistance ion pathways joining excitable cells (nerve and muscle), gap junctions are found joining virtually all cells in solid tissues.
Daniel A, Goodenough, David L, Paul
openaire   +3 more sources

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