Connexin 30 expression and frequency of connexin heterogeneity in astrocyte gap junction plaques increase with age in the rat retina. [PDF]
We investigated age-associated changes in retinal astrocyte connexins (Cx) by assaying Cx numbers, plaque sizes, protein expression levels and heterogeneity of gap junctions utilizing six-marker immunohistochemistry (IHC).
Hussein Mansour +5 more
doaj +1 more source
Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies [PDF]
We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments.
Johnson, Ross G. +3 more
core +2 more sources
Gap Junctions in Ischemia-Related Ventricular Arrhythmia
Cardiovascular diseases are the leading cause of death worldwide, with isch-emic heart disease being the most common entity. Ventricular arrhythmia is one of the complications of ischemia that can result in sudden cardiac death.
Berlian Idriansyah Idris, Yoga Yuniadi
doaj +1 more source
The structural organization and protein composition of lens fiber junctions. [PDF]
The structural organization and protein composition of lens fiber junctions isolated from adult bovine and calf lenses were studied using combined electron microscopy, immunolocalization with monoclonal and polyclonal anti-MIP and anti-MP70 (two putative
Ehring, GR +3 more
core +2 more sources
Gap-junctional coupling between neutrophils and endothelial cells [PDF]
Communication between leukocytes and endothelial cells is crucial for inflammatory reactions. Paracrine cross-talk and outside-in signaling (via adhesion molecules) have been characterized as communication pathways to date.
Gloe, Torsten +3 more
core +1 more source
Gap junction networks in mushroom bodies participate in visual learning and memory in Drosophila
Gap junctions are widely distributed in the brains across species and play essential roles in neural information processing. However, the role of gap junctions in insect cognition remains poorly understood.
Qingqing Liu +6 more
doaj +1 more source
Immunocytochemical localization of the main intrinsic polypeptide (MIP) in ultrathin frozen sections of rat lens. [PDF]
The in situ distribution of the 26-kdalton Main Intrinsic Polypeptide (MIP or MP 26), a putative gap junction protein in ocular lens fibers, was defined at the electron microscope level using indirect immunoferritin labeling of ultrathin frozen sections ...
Bok, D, Fitzgerald, PG, Horwitz, J
core +1 more source
Gap junctions: historical discoveries and new findings in the Caenorhabditis elegans nervous system
Gap junctions are evolutionarily conserved structures at close membrane contacts between two cells. In the nervous system, they mediate rapid, often bi-directional, transmission of signals through channels called innexins in invertebrates and connexins ...
Eugene Jennifer Jin +3 more
doaj +1 more source
The 43-kD polypeptide of heart gap junctions: immunolocalization, topology, and functional domains [PDF]
Analysis by SDS-PAGE of gap junction fractions isolated from heart suggests that the junctions are comprised of a protein with an Mr 43,000. Antibodies against the electroeluted protein and a peptide representing the 20 amino terminal residues bind ...
Austin, Brian J. +4 more
core +1 more source
Gap junction-mediated regulation of endothelial cellular stiffness
Endothelial monolayers have shown the ability to signal each other through gap junctions. Gap junction-mediated cell-cell interactions have been implicated in the modulation of endothelial cell functions during vascular inflammation.
Takayuki Okamoto +7 more
doaj +1 more source

