Results 21 to 30 of about 98,351 (351)

Defining gap junctions [PDF]

open access: yesThe Journal of Cell Biology, 2005
In the 1960s there was adhesion and there was direct current transfer—a strange neuronal phenomenon whose mechanism was unknown. The two fields only gradually drifted together, but with the report by Revel and Karnovsky (1967) they were united around a distinct, structural correlate soon to ...
William A, Wells, Laura, Bonetta
openaire   +2 more sources

Analysis of rod/cone gap junctions from the reconstruction of mouse photoreceptor terminals

open access: yeseLife, 2022
Electrical coupling, mediated by gap junctions, contributes to signal averaging, synchronization, and noise reduction in neuronal circuits. In addition, gap junctions may also provide alternative neuronal pathways.
Munenori Ishibashi   +10 more
doaj   +1 more source

Regulation of Gap Junction Dynamics by UNC-44/ankyrin and UNC-33/CRMP through VAB-8 in C. elegans Neurons. [PDF]

open access: yesPLoS Genetics, 2016
Gap junctions are present in both vertebrates and invertebrates from nematodes to mammals. Although the importance of gap junctions has been documented in many biological processes, the molecular mechanisms underlying gap junction dynamics remain unclear.
Lingfeng Meng, Chia-hui Chen, Dong Yan
doaj   +1 more source

Gap junctions, dendrites and resonances : a recipe for tuning network dynamics [PDF]

open access: yes, 2013
Gap junctions, also referred to as electrical synapses, are expressed along the entire central nervous system and are important in mediating various brain rhythms in both normal and pathological states.
Michieletto, Davide   +5 more
core   +1 more source

Connexins in neurons and glia: targets for intervention in disease and injury

open access: yesNeural Regeneration Research, 2015
Both neurons and glia throughout the central nervous system are organized into networks by gap junctions. Among glia, gap junctions facilitate metabolic homeostasis and intercellular communication.
Keith B Moore, John O′Brien
doaj   +1 more source

Connexin hemichannels as candidate targets for cardioprotective and anti-arrhythmic treatments

open access: yesThe Journal of Clinical Investigation, 2023
Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap junctions are responsible for the propagation of electrical and chemical signals between myocardial cells and cells of the specialized conduction system in order to ...
Luc Leybaert   +8 more
doaj   +1 more source

Nitric oxide enhances de novo formation of endothelial gap junctions [PDF]

open access: yes, 2003
Objective: Gap junctions (formed by connexins, Cx) are important for functional coordination of cells in the vascular wall. However, little is known about their physiological regulation in this tissue.
Gloe, Torsten   +3 more
core   +1 more source

Abundance of gap junctions at glutamatergic mixed synapses in adult Mosquitofish spinal cord neurons

open access: yesFrontiers in Neural Circuits, 2014
Dye-coupling, whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the ...
Jose L Serrano-Velez   +8 more
doaj   +1 more source

Studying gap junctions with PARIS

open access: yeseLife, 2019
A new genetically encoded system manipulates the pH inside cells to detect whether they are coupled to each other.
Daniel R Kick, David J Schulz
doaj   +1 more source

Analysis of Hemichannels and Gap Junctions: Application and Extension of the Passive Transmembrane Ion Transport Model

open access: yesFrontiers in Cellular Neuroscience, 2021
Electrical synaptic transmission is an essential form of interneuronal communication which is mediated by gap junctions that permit ion flow. Three gene families (connexins, innexins, and pannexins) have evolved to form gap junctional channels.
Qiqian Wang, Shenquan Liu
doaj   +1 more source

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