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Cell communication and immunology: part 2 [Frontiers of biomedical engineering]

, 2011
Presents the lecture Professor Saltzman. He continues his discussion of cell communication in the body, extending the description to the nervous and immune system.
Saltzman, W. Mark
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Two homologous Agr-like quorum-sensing systems cooperatively control adherence, cell morphology, and cell viability properties in Lactobacillus plantarum WCFS1

, 2008
A two-component regulatory system of Lactobacillus plantarum, encoded by genes designated lamK and lamR (hpk10 and rrp10), was studied. The lamK and lamR genes encode proteins which are highly homologous to the quorum-sensing histidine kinase LamC and ...
Vos, W.M., de, Kleerebezem, M., Kunuki, Ryoko, Ingham, C.J., Sturme, Mark, Nakayama, J., Vaughan, Elaine, Kunuki, R., Nakayama, Jiro, Sturme, M.H.J., Fujii, Toshio, Kleerebezem, Michiel, Molenaar, D., Fujii, T., Vaughan, E.E., Ingham, Colin, Beerthuyzen, Marke, Molenaar, Douwe, de Vos, Willem, Molenaar, Douwe; id_orcid, de Vos, W.M., Beerthuyzen, M.M.   +21 more
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'Special K' and a loss of cell-to-cell adhesion in proximal tubule-derived epithelial cells : modulation of the adherens junction complex by ketamine [PDF]

, 2013
Ketamine, a mild hallucinogenic class C drug, is the fastest growing ‘party drug’ used by 16–24 year olds in the UK. As the recreational use of Ketamine increases we are beginning to see the signs of major renal and bladder complications. To date however,
Claire E Hills, Hills Claire E., Jefferson Kieran P., Squires, Paul E., Issac K-K Liu, Tianrong Jin (452021), Jefferson, Kieran P., Liu, Kuo-Kang, Siamantouras Eleftherios, Siamantouras, Eleftherios, Claire E. Hills (452020), Hills, Claire E., Jin, Tianrong, Eleftherios Siamantouras, Paul E. Squires (452025), Jin Tianrong, Issac K-K Liu (452023), Squires Paul E., Tianrong Jin, Paul E Squires, Liu Issac K-K, Kieran P Jefferson, Kieran P. Jefferson (452024), Eleftherios Siamantouras (452022)   +23 more
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Unraveling the emerging role of glial heterogeneity in neuropathic pain: from pathological mechanisms to therapeutic Frontiers

Frontiers in Neurology
Neuropathic pain (NP) arises from injury or dysfunction within the somatosensory nervous system and represents a major clinical challenge due to its complex and multifactorial pathogenesis.
Zhiwei Li, Jiafeng Lu, Zhonghua Chen
doaj   +1 more source

T Cell Microvilli: Sensors or Senders?

Frontiers in Immunology, 2019
Communication between cells is essential for multicellular life. During cognate immune interactions, T cells communicate with antigen-presenting cells (APC) via direct cell–cell contact or the release of molecules and vesicles containing T cell messages.
Hye-Ran Kim, Hye-Ran Kim, Chang-Duk Jun, Chang-Duk Jun   +3 more
doaj   +1 more source

Intrinsically Disordered Proteins Play Diverse Roles in Cell Signaling

, 2022
Signaling pathways allow cells to detect and respond to a wide variety of chemical (e.g. Ca2+ or chemokine proteins) and physical stimuli (e.g., sheer stress, light).
Uversky, Vladimir N., Dunker, A. Keith, Bondos, Sarah E.   +2 more
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Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation

Frontiers in Immunology
BackgroundOsteosarcoma (OS) is one of the most common primary malignant bone tumors, primarily originating from mesenchymal tissue. It is notorious for its high invasiveness, high disability rate, high mortality rate, and poor prognosis.
Lei Sun, Jinhao Zhang, Zhikai Xiahou, Zhenzhen Zhao, Yanchen Liang   +4 more
doaj   +1 more source

Tissue‐Specific Extracellular Vesicles Enriched From Circulation: Exploring the Liquid Biopsy Perspective

Journal of Extracellular Biology
Extracellular vesicles (EVs) released from tissues can be found in human biofluids. EVs reflect the phenotypic state of their cell of origin, carrying informative molecular biomarkers within and between tissues, and represent a promising target for ...
Biancamaria Pierri, Erez Eitan, Kenneth W. Witwer, Diane B. Re, Andrea A. Baccarelli, Haotian Wu   +5 more
doaj   +1 more source

The role of SASP in ischemic stroke: a deep dive into cellular mechanisms

Frontiers in Neurology
BackgroundThe escalating incidence of ischemic stroke (IS) exerts a heavy toll on global health. Aging, a prominent risk factor, implicates the senescence-associated secretory phenotype (SASP) in IS pathogenesis.
Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang   +3 more
doaj   +1 more source

Cell-cell communication in three dimensional microenvironments

, 2011
Cellular behavior is dependent on a variety of extracellular cues required for normal tissue function, wound healing, and activation of the immune system.
Trump, Lisa R.
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