Results 1 to 10 of about 221,929 (293)

Connexins in neurons and glia: targets for intervention in disease and injury

Neural Regeneration Research, 2015
Both neurons and glia throughout the central nervous system are organized into networks by gap junctions. Among glia, gap junctions facilitate metabolic homeostasis and intercellular communication.
Keith B Moore, John O′Brien
doaj   +1 more source

Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface

Veterinary Research, 2019
Intestinal epithelium functions as a barrier to protect multicellular organisms from the outside world. It consists of epithelial cells closely connected by intercellular junctions, selective gates which control paracellular diffusion of solutes, ions ...
Tingting Cui, Sebastiaan Theuns, Jiexiong Xie, Hans J. Nauwynck   +3 more
doaj   +1 more source

Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation

Biomolecules, 2019
Adherens junctions, consisting of cadherins and catenins, are a group of cell-to-cell junctions that mediate mechanistic linkage between neighboring cells. By doing so, adherens junctions ensure direct intercellular contact and play an indispensable role
Raf Van Campenhout, Sara Crespo Yanguas, Axelle Cooreman, Eva Gijbels, Kaat Leroy, Vânia Vilas-Boas, Nick Devoogdt, Serge Muyldermans, Bruno Cogliati, Mathieu Vinken   +9 more
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Force-driven growth of intercellular junctions [PDF]

Journal of Theoretical Biology, 2017
11 pages, 12 figures, 2 ...
Tehrani, Mohammad, Sarvestani, Alireza S.   +1 more
openaire   +4 more sources

Effect Of Gas6 On Endothelial Barrier Induced By Pg-Lps

International Dental Journal
Aim or purpose: To explore the function of Growth-arrest-specific protein 6 (Gas6) on vascular endothelial barrier integrity induced by Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) in human umbilical vein endothelial cells (HUVECs). Materials and
He Chen, Na An, Yingjun Liu
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Interaction Studies Between Cyclic Peptide ADT-C3 (Ac-CADTPC-NH2) with E-Cadherin Protein using the Molecular Docking Method Simulated on 120ns

Jurnal Kimia Sains dan Aplikasi, 2018
The treatment of diseases that attack the brain is very difficult, because the delivery of drug molecules to the brain is often hindered by the blood-brain barrier (BBB). So that the drug delivery is not right on the target cell.
Parsaoran Siahaan, Vivitri Dewi Prasasty, Atiatul Manna, Dwi Hudiyanti   +3 more
doaj   +1 more source

Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size

Frontiers in Ophthalmology
Gap junctions transmit electrical signals in neurons and serve metabolic coupling and chemical communication. Gap junctions are made of intercellular channels with large pores, allowing ions and small molecules to permeate.
Chunxu Yuan, Luca Gerhards, Ilia A. Solov’yov, Ilia A. Solov’yov, Ilia A. Solov’yov, Karin Dedek, Karin Dedek   +6 more
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Intercellular Diffusion of a Fluorescent Sucrose Analog via the Septal Junctions in a Filamentous Cyanobacterium

mBio, 2015
Many filamentous cyanobacteria produce specialized nitrogen-fixing cells called heterocysts, which are located at semiregular intervals along the filament with about 10 to 20 photosynthetic vegetative cells in between.
Dennis J. Nürnberg, Vicente Mariscal, Jan Bornikoel, Mercedes Nieves-Morión, Norbert Krauß, Antonia Herrero, Iris Maldener, Enrique Flores, Conrad W. Mullineaux   +8 more
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ATP Release from Cultured Endothelial Cells and Intercellular Calcium Signaling during Shear Stress Exposure

Journal of Biomechanical Science and Engineering, 2009
Intracellular calcium ([Ca2+]i) is a second messenger molecule critical for numerous intracellular signaling pathways in endothelial cells (ECs). Direct mechanical stimulation imposed on single ECs by a microprobe has been demonstrated to increase [Ca2 ...
Susumu KUDO, Kaoru HOSOE, Makoto HOSOBUCHI, Naoto KAWASAKI, Kazuo TANISHITA   +4 more
doaj   +1 more source

Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling

Experimental and Molecular Medicine
s Circulating tumor cell (CTC) clusters, key in metastasis, rely on intercellular junctions for stability. However, the specific mechanisms governing intercellular connections within CTC clusters and the strategy targeting intercellular junctions to ...
Jueyao Zou, Junfeng Shi, Qiong Chen, Ziyan Zhu, Tongyao Hu, Zhengyu Zhang, Zhiqiang Pan, Fei Xu, Yong Zhu, Yuanyuan Wu, Yang Zhao, Aiyun Wang, Yin Lu, Yanhong Pan, Wenxing Chen   +14 more
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