Results 41 to 50 of about 44,455 (257)

Effect Of Gas6 On Endothelial Barrier Induced By Pg-Lps

International Dental Journal
Aim or purpose: To explore the function of Growth-arrest-specific protein 6 (Gas6) on vascular endothelial barrier integrity induced by Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) in human umbilical vein endothelial cells (HUVECs). Materials and
He Chen, Na An, Yingjun Liu
doaj   +1 more source

Interaction Studies Between Cyclic Peptide ADT-C3 (Ac-CADTPC-NH2) with E-Cadherin Protein using the Molecular Docking Method Simulated on 120ns

Jurnal Kimia Sains dan Aplikasi, 2018
The treatment of diseases that attack the brain is very difficult, because the delivery of drug molecules to the brain is often hindered by the blood-brain barrier (BBB). So that the drug delivery is not right on the target cell.
Parsaoran Siahaan, Vivitri Dewi Prasasty, Atiatul Manna, Dwi Hudiyanti   +3 more
doaj   +1 more source

Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size

Frontiers in Ophthalmology
Gap junctions transmit electrical signals in neurons and serve metabolic coupling and chemical communication. Gap junctions are made of intercellular channels with large pores, allowing ions and small molecules to permeate.
Chunxu Yuan, Luca Gerhards, Ilia A. Solov’yov, Ilia A. Solov’yov, Ilia A. Solov’yov, Karin Dedek, Karin Dedek   +6 more
doaj   +1 more source

Intercellular Diffusion of a Fluorescent Sucrose Analog via the Septal Junctions in a Filamentous Cyanobacterium

mBio, 2015
Many filamentous cyanobacteria produce specialized nitrogen-fixing cells called heterocysts, which are located at semiregular intervals along the filament with about 10 to 20 photosynthetic vegetative cells in between.
Dennis J. Nürnberg, Vicente Mariscal, Jan Bornikoel, Mercedes Nieves-Morión, Norbert Krauß, Antonia Herrero, Iris Maldener, Enrique Flores, Conrad W. Mullineaux   +8 more
doaj   +1 more source

ATP Release from Cultured Endothelial Cells and Intercellular Calcium Signaling during Shear Stress Exposure

Journal of Biomechanical Science and Engineering, 2009
Intracellular calcium ([Ca2+]i) is a second messenger molecule critical for numerous intracellular signaling pathways in endothelial cells (ECs). Direct mechanical stimulation imposed on single ECs by a microprobe has been demonstrated to increase [Ca2 ...
Susumu KUDO, Kaoru HOSOE, Makoto HOSOBUCHI, Naoto KAWASAKI, Kazuo TANISHITA   +4 more
doaj   +1 more source

Visfatin reduces gap junction mediated cell-to-cell communication in proximal tubule-derived epithelial cells [PDF]

, 2013
Background/Aims: In the current study we examined if the adipocytokine, visfatin, alters connexin-mediated intercellular communication in proximal tubule-derived epithelial cells.
Hills, Claire E., Kerr, Michael I., Squires, Paul E., Wall, Mark J.   +3 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hirudin suppresses hematogenous metastasis by targeting desmosome junction transition in circulating tumor cell clusters via HIF-1α–DSG2 signaling

Experimental and Molecular Medicine
s Circulating tumor cell (CTC) clusters, key in metastasis, rely on intercellular junctions for stability. However, the specific mechanisms governing intercellular connections within CTC clusters and the strategy targeting intercellular junctions to ...
Jueyao Zou, Junfeng Shi, Qiong Chen, Ziyan Zhu, Tongyao Hu, Zhengyu Zhang, Zhiqiang Pan, Fei Xu, Yong Zhu, Yuanyuan Wu, Yang Zhao, Aiyun Wang, Yin Lu, Yanhong Pan, Wenxing Chen   +14 more
doaj   +1 more source

Protective effects of HBOC on pulmonary vascular leakage after haemorrhagic shock and the underlying mechanisms

Artificial Cells, Nanomedicine, and Biotechnology, 2020
Volume resuscitation is an important early treatment for haemorrhagic shock. Haemoglobin-based oxygen carrier (HBOC) can expand the volume and provide oxygen for tissues.
Hong Liang Zhao, Jie Zhang, Yu Zhu, Yue Wu, Qing Guang Yan, Xiao Yong Peng, Xin Ming Xiang, Kun Lun Tian, Tao Li, Liang Ming Liu   +9 more
doaj   +1 more source

PP2A-B55alpha controls keratinocyte adhesion through dephosphorylation of the Desmoplakin C-terminus

Scientific Reports, 2023
Critical for the maintenance of epidermal integrity and function are attachments between intermediate filaments (IF) and intercellular junctions called desmosomes.
Abbey L. Perl, Jennifer L. Koetsier, Kathleen J. Green   +2 more
doaj   +1 more source