Results 41 to 50 of about 27,235 (248)
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
El hedor en la Nueva España: sensibilidad olfativa ante el fenómeno de la otredad (siglo XVI)
Historia CríticaObjective/Context: This article aims to analyze the olfactory descriptions of blood, the Indigenous, and their idols in sacrificial narratives in four early modern American sources (sixteenth century): Letters of Relation by Hernán Cortés, The Vision of ...
Ingrid Sánchez Téllez
doaj +1 more source
Why emerging leaders should focus on being good postdoctoral supervisors
FEBS Letters, EarlyView.Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski +5 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study challenges the idea that Sit4‐associated protein subunit 3 (SAPS3) inhibits the energy‐sensing enzyme AMP‐activated protein kinase (AMPK) in muscle and liver tissue. Although SAPS3 interacts with AMPK in cultured cells, we found no such interaction in human or mouse tissues subjected to fasting, exercise, or a high‐fat diet.
Jesper B. Birk +3 more
wiley +1 more source
Études romanes de Brno, 2018 En los capítulos CLXXXV-CLXXXVIII (185 y 188) de Historia verdadera de la conquista de la Nueva España (1632) Bernal Díaz del Castillo describe a la misma mujer —Juana de Mansilla— como hechicera y como matrona romana.
Silvia Ruiz Tresgallo
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Revista Chilena de Literatura, 2010 El presente artículo proporciona una lectura actualizada de las llamadas ‘novelas históricas’ o ‘novelas de ciudad’ de Carlos Droguett. En particular, sus novelas centradas en la conquista y fundación de la ciudad de Santiago (100 gotas de sangre y 200 ...
Roberto Suazo Gómez
doaj
Continuidades históricas en la conquista de América [PDF]
Revista Colombiana de Ciencias Sociales, 2016 El trabajo busca proporcionar una imagen de síntesis del proceso de la conquista de América. Se destaca el enorme cambio cultural generado desde la conquista, como las tendencias de continuidad del proceso histórico en mención.
Felipe Cárdenas Tamara
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source